Caloric restriction mimetics against age-associated disease: targets, mechanisms, and therapeutic potential

F Madeo, D Carmona-Gutierrez, SJ Hofer, G Kroemer - Cell metabolism, 2019 - cell.com
The increase in life expectancy has boosted the incidence of age-related pathologies
beyond social and economic sustainability. Consequently, there is an urgent need for …

[HTML][HTML] Nrf2 signaling pathway: Pivotal roles in inflammation

SMU Ahmed, L Luo, A Namani, XJ Wang… - Biochimica et Biophysica …, 2017 - Elsevier
Inflammation is the most common feature of many chronic diseases and complications, while
playing critical roles in carcinogenesis. Several studies have demonstrated that Nrf2 …

[HTML][HTML] The safety of green tea and green tea extract consumption in adults–results of a systematic review

J Hu, D Webster, J Cao, A Shao - Regulatory toxicology and pharmacology, 2018 - Elsevier
A systematic review of published toxicology and human intervention studies was performed
to characterize potential hazards associated with consumption of green tea and its …

[HTML][HTML] Mitochondrial dysfunction and insulin resistance: an update

MK Montgomery, N Turner - Endocrine connections, 2015 - ec.bioscientifica.com
Mitochondrial dysfunction has been implicated in the development of insulin resistance (IR);
however, a large variety of association and intervention studies as well as genetic …

Mechanisms of body weight reduction and metabolic syndrome alleviation by tea

CS Yang, J Zhang, L Zhang, J Huang… - Molecular nutrition & …, 2016 - Wiley Online Library
Tea, a popular beverage made from leaves of the plant Camellia sinensis, has been shown
to reduce body weight, alleviate metabolic syndrome, and prevent diabetes and …

Molecular understanding of Epigallocatechin gallate (EGCG) in cardiovascular and metabolic diseases

QY Eng, PV Thanikachalam, S Ramamurthy - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance The compound epigallocatechin-3-gallate (EGCG), the
major polyphenolic compound present in green tea [Camellia sinensis (Theaceae], has …

Anti-obesogenic and antidiabetic effects of plants and mushrooms

J Martel, DM Ojcius, CJ Chang, CS Lin, CC Lu… - Nature Reviews …, 2017 - nature.com
Obesity is reaching global epidemic proportions as a result of factors such as high-calorie
diets and lack of physical exercise. Obesity is now considered to be a medical condition …

Scientific opinion on the safety of green tea catechins

EFSA Panel on Food Additives and Nutrient … - EFSA …, 2018 - Wiley Online Library
Abstract The EFSA ANS Panel was asked to provide a scientific opinion on the safety of
green tea catechins from dietary sources including preparations such as food supplements …

Epigallocatechin gallate: Phytochemistry, bioavailability, utilization challenges, and strategies

S Mehmood, M Maqsood, N Mahtab… - Journal of Food …, 2022 - Wiley Online Library
Epigallocatechin gallate (EGCG), a green tea catechin, has gained the attention of current
study due to its excellent health‐promoting effects. It possesses anti‐obesity, antimicrobial …

Beneficial effects of tea and the green tea catechin epigallocatechin-3-gallate on obesity

T Suzuki, M Pervin, S Goto, M Isemura, Y Nakamura - Molecules, 2016 - mdpi.com
Green tea has been shown to have beneficial effects against cancer, obesity,
atherosclerosis, diabetes, bacterial and viral infections, and dental caries. The catechin (−) …