Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease
Summary Sporadic Creutzfeldt-Jakob disease is a fatal neurodegenerative disease caused
by misfolded prion proteins (PrP Sc). Effective therapeutics are currently not available and …
by misfolded prion proteins (PrP Sc). Effective therapeutics are currently not available and …
Rapidly progressive dementias—aetiologies, diagnosis and management
Rapidly progressive dementias (RPDs) are a group of heterogeneous disorders that include
immune-mediated, infectious and metabolic encephalopathies, as well as prion diseases …
immune-mediated, infectious and metabolic encephalopathies, as well as prion diseases …
Sporadic human prion diseases: molecular insights and diagnosis
Human prion diseases can be sporadic, inherited, or acquired by infection. Distinct clinical
and pathological characteristics separate sporadic diseases into three phenotypes …
and pathological characteristics separate sporadic diseases into three phenotypes …
Creutzfeldt-Jakob disease: updated diagnostic criteria, treatment algorithm, and the utility of brain biopsy
Creutzfeldt-Jakob disease (CJD) is a rare neurodegenerative condition with a rapid disease
course and a mortality rate of 100%. Several forms of the disease have been described, and …
course and a mortality rate of 100%. Several forms of the disease have been described, and …
Prion diseases
MD Geschwind - CONTINUUM: Lifelong Learning in Neurology, 2015 - journals.lww.com
Abstract Purpose of Review: This article presents an update on the clinical aspects of human
prion disease, including the wide spectrum of their presentations. Recent Findings: Prion …
prion disease, including the wide spectrum of their presentations. Recent Findings: Prion …
Movement disorders with neuronal antibodies: syndromic approach, genetic parallels and pathophysiology
Movement disorders are a prominent and common feature in many autoantibody-associated
neurological diseases, a group of potentially treatable conditions that can mimic infectious …
neurological diseases, a group of potentially treatable conditions that can mimic infectious …
Imaging of Creutzfeldt-Jakob disease: imaging patterns and their differential diagnosis
DC Fragoso, ALM Gonçalves Filho, FT Pacheco… - Radiographics, 2017 - pubs.rsna.org
Diagnosis of sporadic Creutzfeldt-Jakob disease (sCJD) remains a challenge because of
the large variability of the clinical scenario, especially in its early stages, which may mimic …
the large variability of the clinical scenario, especially in its early stages, which may mimic …
Rapidly progressive dementia
MD Geschwind - Continuum: Lifelong Learning in Neurology, 2016 - journals.lww.com
Abstract Purpose of Review: This article presents a practical and informative approach to the
evaluation of a patient with a rapidly progressive dementia (RPD). Recent Findings: Prion …
evaluation of a patient with a rapidly progressive dementia (RPD). Recent Findings: Prion …
Validation of revised international Creutzfeldt-Jakob disease surveillance network diagnostic criteria for sporadic Creutzfeldt-Jakob disease
N Watson, P Hermann, A Ladogana… - JAMA network …, 2022 - jamanetwork.com
Importance Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly lethal disease. Rapid,
accurate diagnosis is imperative for epidemiological surveillance and public health activities …
accurate diagnosis is imperative for epidemiological surveillance and public health activities …
Advanced tests for early and accurate diagnosis of Creutzfeldt–Jakob disease
G Zanusso, S Monaco, M Pocchiari… - Nature Reviews …, 2016 - nature.com
Early and accurate diagnosis of Creutzfeldt–Jakob disease (CJD) is a necessary to
distinguish this untreatable disease from treatable rapidly progressive dementias, and to …
distinguish this untreatable disease from treatable rapidly progressive dementias, and to …