Taurine as a natural antioxidant: From direct antioxidant effects to protective action in various toxicological models

PF Surai, K Earle-Payne, MT Kidd - Antioxidants, 2021 - mdpi.com
Natural antioxidants have received tremendous attention over the last 3 decades. At the
same time, the attitude to free radicals is slowly changing, and their signalling role in …

[HTML][HTML] Effects and mechanisms of taurine as a therapeutic agent

S Schaffer, HW Kim - Biomolecules & therapeutics, 2018 - ncbi.nlm.nih.gov
Taurine is an abundant, β-amino acid with diverse cytoprotective activity. In some species,
taurine is an essential nutrient but in man it is considered a semi-essential nutrient, although …

The physiopathologic role of oxidative stress in skeletal muscle

BM Scicchitano, L Pelosi, G Sica, A Musarò - Mechanisms of Ageing and …, 2018 - Elsevier
Muscle senescence is a complex mechanism that is usually associated with a decrease in
mass, strength and velocity of contraction. This state, known as sarcopenia, is a multifactorial …

Multifunctional Hydrogel Microneedle Patches Modulating Oxi‐inflamm‐aging for Diabetic Wound Healing

S Tian, J Mei, L Zhang, S Wang, Y Yuan, J Li, H Liu… - Small, 2024 - Wiley Online Library
Oxidative stress, chronic inflammation, and immune senescence are important pathologic
factors in diabetic wound nonhealing. This study loads taurine (Tau) into cerium dioxide …

A distinct pattern of circulating amino acids characterizes older persons with physical frailty and sarcopenia: results from the BIOSPHERE study

R Calvani, A Picca, F Marini, A Biancolillo, J Gervasoni… - Nutrients, 2018 - mdpi.com
Physical frailty and sarcopenia (PF&S) are hallmarks of aging that share a common
pathogenic background. Perturbations in protein/amino acid metabolism may play a role in …

[HTML][HTML] Taurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70

GF Abud, FG De Carvalho, G Batitucci, SG Travieso… - Nutrition, 2022 - Elsevier
Objective Based on the antioxidant effects of taurine, which are capable of controlling
oxidative stress in the aging process, the aim of this study was to investigate the effects of …

Taurine activates the AKT–mTOR axis to restore muscle mass and contractile strength in human 3D in vitro models of steroid myopathy

S Mughal, M Sabater-Arcis, R Artero… - Disease Models & …, 2024 - journals.biologists.com
Steroid myopathy is a clinically challenging condition exacerbated by prolonged
corticosteroid use or adrenal tumors. In this study, we engineered a functional three …

Age-related alterations at neuromuscular junction: role of oxidative stress and epigenetic modifications

G Dobrowolny, A Barbiera, G Sica, BM Scicchitano - Cells, 2021 - mdpi.com
With advancing aging, a decline in physical abilities occurs, leading to reduced mobility and
loss of independence. Although many factors contribute to the physio-pathological effects of …

Pre/postnatal taurine supplementation improves neurodevelopment and brain function in mice offspring: A persistent developmental study from puberty to maturity

MM Ommati, H Rezaei, RM Socorro, W Tian, J Zhao… - Life Sciences, 2024 - Elsevier
Taurine (TAU) is a sulfur-containing amino acid abundantly found in the human body.
Endogenously, TAU is synthesized from cysteine in the liver. However, newborns rely …

Identification of a circulating amino acid signature in frail older persons with type 2 diabetes mellitus: Results from the metabofrail study

R Calvani, L Rodriguez-Mañas, A Picca, F Marini… - Nutrients, 2020 - mdpi.com
Diabetes and frailty are highly prevalent conditions that impact the health status of older
adults. Perturbations in protein/amino acid metabolism are associated with both functional …