[HTML][HTML] Cervical cancer in low and middle‑income countries

R Hull, M Mbele, T Makhafola, C Hicks… - Oncology …, 2020 - spandidos-publications.com
Cervical cancer is a malignant tumour that occurs in the cervix and is classified into two
histological types, adenocarcinoma and squamous cell carcinoma (SCC); SCC is more …

Non-coding RNA networks in cancer

E Anastasiadou, LS Jacob, FJ Slack - Nature Reviews Cancer, 2018 - nature.com
Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …

LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer

Y Wang, JH Lu, QN Wu, Y Jin, DS Wang, YX Chen… - Molecular cancer, 2019 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) play nonnegligible roles in the
epigenetic regulation of cancer cells. This study aimed to identify a specific lncRNA that …

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase

DA Ruess, GJ Heynen, KJ Ciecielski, J Ai… - Nature medicine, 2018 - nature.com
The ubiquitously expressed non-receptor protein tyrosine phosphatase SHP2, encoded by
PTPN11, is involved in signal transduction downstream of multiple growth factor, cytokine …

The role of long noncoding RNAs in hepatocellular carcinoma

Z Huang, JK Zhou, Y Peng, W He, C Huang - Molecular cancer, 2020 - Springer
Hepatocellular carcinoma (HCC) is the most frequent subtype of primary liver cancer and
one of the leading causes of cancer-related death worldwide. However, the molecular …

Long noncoding RNA MALAT1 regulates autophagy associated chemoresistance via miR-23b-3p sequestration in gastric cancer

H YiRen, Y YingCong, Y Sunwu, L Keqin, T Xiaochun… - Molecular cancer, 2017 - Springer
Background Chemoresistance has long been recognized as a major obstacle in cancer
therapy. Clarifying the underlying mechanism of chemoresistance would result in novel …

Induction of m6A methylation in adipocyte exosomal LncRNAs mediates myeloma drug resistance

Z Wang, J He, D Bach, Y Huang, Z Li, H Liu… - Journal of Experimental …, 2022 - Springer
Background Therapeutic resistance occurs in most patients with multiple myeloma (MM).
One of the key mechanisms for MM drug resistance comes from the interaction between MM …

[HTML][HTML] The LPS-inducible lncRNA Mirt2 is a negative regulator of inflammation

M Du, L Yuan, X Tan, D Huang, X Wang… - Nature …, 2017 - nature.com
Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRR) with a crucial
function in innate immune responses. Activation of TLR4 signaling at the plasma membrane …

lncRNASNP2: an updated database of functional SNPs and mutations in human and mouse lncRNAs

YR Miao, W Liu, Q Zhang, AY Guo - Nucleic acids research, 2018 - academic.oup.com
Long non-coding RNAs (lncRNAs) are emerging as important regulators in different
biological processes through various ways. Because the related data, especially mutations …

LINC00673 is activated by YY1 and promotes the proliferation of breast cancer cells via the miR-515-5p/MARK4/Hippo signaling pathway

K Qiao, S Ning, L Wan, H Wu, Q Wang, X Zhang… - Journal of Experimental …, 2019 - Springer
Background An increasing number of studies have shown that long noncoding RNAs
(lncRNAs) play essential roles in tumor initiation and progression. LncRNAs act as tumor …