Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …

The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

The COVID-19 pandemic caused by the SARS-CoV-2 virus remains a global public health
crisis. Although widespread vaccination campaigns are underway, their efficacy is reduced …

TMPRSS2 is a type II transmembrane protease with broad expression in epithelial cells of
the respiratory and gastrointestinal tract, the prostate, and other organs. Although the …

With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the
first documented pandemic due to a coronavirus that continues to be a major health …

Target prediction and virtual screening are two powerful tools of computer-aided drug
design. Target identification is of great significance for hit discovery, lead optimization, drug …

Ophthalmic neurodegenerative diseases encompass a wide array of molecular pathologies
unified by calpain dysregulation. Calpains are calcium-dependent proteases that perpetuate …

Plasmodium sporozoites invade hepatocytes, transform into liver stages, and replicate into
thousands of merozoites that infect erythrocytes and cause malaria. Proteins secreted from …

Host cell entry of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is
facilitated via priming of its spike glycoprotein by the human transmembrane protease serine …

Introduction Acute pancreatitis (AP) is the leading cause of hospitalization among
gastrointestinal disorders. The aim of our study is to compare the results between AP …