The classical role of AMP-activated protein kinase (AMPK) is as a cellular energy sensor
activated by falling energy status, signalled by increases in AMP to ATP and ADP to ATP …

Since the discovery of AMP-activated protein kinase (AMPK) as a central regulator of energy
homeostasis, many exciting insights into its structure, regulation and physiological roles …

Skeletal muscle possesses a remarkable ability to adapt to various physiologic conditions.
AMPK is a sensor of intracellular energy status that maintains energy stores by fine-tuning …

Sirt1 is the most prominent and extensively studied member of sirtuins, the family of
mammalian class III histone deacetylases heavily implicated in health span and longevity …

The majority of human energy metabolism occurs in skeletal muscle mitochondria
emphasizing the importance of understanding the regulation of myocellular mitochondrial …

Skeletal muscle plays an important role in regulating whole-body energy expenditure given
it is a major site for glucose and lipid oxidation. Obesity and type 2 diabetes are causally …

Abstract Ethnopharmacological relevance Mulberry (Morus alba L.) leaves have been
widely applied to controlling blood glucose as a efficacious traditional Chinese medicine or …

Dietary restriction can extend life span in most organisms tested to date, suggesting that
mechanisms sensing nutrient and energy availability might regulate longevity. The AMP …

According to the World Health Organization (WHO) polycystic ovary syndrome (PCOS)
occurs in 4–8% of women worldwide. The prevalence of PCOS in Indian adolescents is …

Duchenne muscular dystrophy (DMD) is characterized by myofiber death from apoptosis or
necrosis, leading in many patients to fatal respiratory muscle weakness. Among other …