Abstract Development of the retinal vasculature is based on highly coordinated signalling
between different cell types of the retina, integrating internal metabolic requirements with …

The mouse retina has been used extensively over the past decades to study both
physiologic and pathologic angiogenesis. Over time, various mouse retina models have …

Purpose.: Although diabetic retinopathy (DR) is clinically diagnosed based on vascular
pathology, diabetic patients with angiographically normal retinas have been found to exhibit …

Purpose.: Neuronal and glial alterations precede the overt vascular change that
characterizes diabetic retinopathy. Because retinal astrocytes modulate neuronal and …

Diabetes has become more common in recent years worldwide, and this growth is projected
to continue in the future. The primary concern with diabetes is developing various …

Ischemic retinopathies, such as diabetic retinopathy (DR), retinopathy of prematurity and
retinal vein occlusion are a major cause of blindness in developed nations worldwide. Each …

Background Retinal ischemia results in neuronal degeneration and contributes to the
pathogenesis of multiple blinding diseases. Recently, the fumaric acid ester dimethyl …

Diseases of the retina are the leading causes of blindness in the industrialized world. The
recognition that animals develop retinal diseases with similar traits to humans has led to not …

Neovascularization associated with diabetic retinopathy (DR) and other ocular disorders is a
leading cause of visual impairment and adult-onset blindness. Currently available …

Blood vessels in the developing retina are formed in concert with neural growth, resulting in
functional neurovascular network. Disruption of the neurovascular coordination contributes …