Harnessing nanomaterials for cancer sonodynamic immunotherapy

S Liang, J Yao, D Liu, L Rao, X Chen… - Advanced …, 2023 - Wiley Online Library
Immunotherapy has made remarkable strides in cancer therapy over the past decade.
However, such emerging therapy still suffers from the low response rates and immune …

Recent advances on modulation of H2O2 in tumor microenvironment for enhanced cancer therapeutic efficacy

Z Chu, J Yang, W Zheng, J Sun, W Wang… - Coordination Chemistry …, 2023 - Elsevier
Due to the rapid proliferation of tumors, the hydrogen peroxide (H 2 O 2) concentration of
tumor cells is higher than that of normal cells, which can be used as an effective target for …

Co‐based Nanozymatic Profiling: Advances Spanning Chemistry, Biomedical, and Environmental Sciences

J Li, X Cai, P Jiang, H Wang, S Zhang, T Sun… - Advanced …, 2024 - Wiley Online Library
Nanozymes, next‐generation enzyme‐mimicking nanomaterials, have entered an era of
rational design; among them, Co‐based nanozymes have emerged as captivating players …

Reactive oxygen species scavenging nanomedicine for the treatment of ischemic heart disease

Z Zhang, R Dalan, Z Hu, JW Wang… - Advanced …, 2022 - Wiley Online Library
Ischemic heart disease (IHD) is the leading cause of disability and mortality worldwide.
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …

Rational design of platinum–bismuth sulfide Schottky heterostructure for sonocatalysis‐mediated hydrogen therapy

M Yuan, S Liang, L Yang, F Li, B Liu, C Yang… - Advanced …, 2023 - Wiley Online Library
Conventional sonodynamic therapy is unavoidably limited by the tumor microenvironment,
although many sonosensitizers have been developed to improve them to a certain extent …

Cancer cell membrane-coated C-TiO2 hollow nanoshells for combined sonodynamic and hypoxia-activated chemotherapy

S Ning, X Dai, W Tang, Q Guo, M Lyu, D Zhu, W Zhang… - Acta biomaterialia, 2022 - Elsevier
Sonodynamic therapy (SDT) is a promising strategy for tumor treatment that satisfies all
requirements of penetrating deep-seated tissues without causing additional trauma …

Lactate‐Oxidase‐Instructed Cancer Diagnosis and Therapy

S Jiang, X Chen, J Lin, P Huang - Advanced Materials, 2023 - Wiley Online Library
Lactate oxidase (LOx) has attracted extensive interest in cancer diagnosis and therapy in
recent years owing to its specific catalysis on l‐lactate; its catalytic process consumes …

Organic sonodynamic materials for combination cancer immunotherapy

C Zhang, K Pu - Advanced Materials, 2023 - Wiley Online Library
Sonodynamic therapy (SDT) is a promising non‐invasive therapeutic modality to treat deep‐
seated tumors owing to the good tissue penetration ability and spatiotemporal controllability …

Chemical Modulation of Glucose Metabolism with a Fluorinated CaCO3 Nanoregulator Can Potentiate Radiotherapy by Programming Antitumor Immunity

Z Dong, C Wang, Y Gong, Y Zhang, Q Fan, Y Hao… - ACS …, 2022 - ACS Publications
Tumor hypoxia and acidity are well-known features in solid tumors that cause
immunosuppression and therapeutic resistance. Herein, we rationally synthesized a …

Engineering lactate-modulating nanomedicines for cancer therapy

J Chen, Y Zhu, C Wu, J Shi - Chemical Society Reviews, 2023 - pubs.rsc.org
Lactate in tumors has long been considered “metabolic junk” derived from the glycolysis of
cancer cells and utilized only as a biomarker of malignancy, but is presently believed to be a …