Viruses, friends, and foes: The case of Torque Teno Virus and the net state of immunosuppression

N Redondo, D Navarro, JM Aguado… - Transplant Infectious …, 2022 - Wiley Online Library
New reliable biomarkers are needed to improve individual risk assessment for post‐
transplant infection, acute graft rejection and other immune‐related complications after solid …

Integrated immunologic monitoring in solid organ transplantation: the road toward torque Teno virus-guided immunosuppression

P Jaksch, I Görzer, E Puchhammer-Stöckl… - Transplantation, 2022 - journals.lww.com
Potent immunosuppressive drugs have been introduced into clinical care for solid organ
transplant recipients. It is now time to guide these drugs on an individual level to optimize …

Torque teno virus load as marker of rejection and infection in solid organ transplantation–A systematic review and meta‐analysis

AL Van Rijn, R Roos, FW Dekker… - Reviews in Medical …, 2023 - Wiley Online Library
Balancing immunosuppression to prevent rejection in solid organ transplant (SOT)
recipients remains challenging. Torque teno virus (TTV), a commensal non‐pathogenic …

[HTML][HTML] Torque teno virus for risk stratification of graft rejection and infection in kidney transplant recipients—a prospective observational trial

K Doberer, M Schiemann, R Strassl… - American Journal of …, 2020 - Elsevier
The nonpathogenic and ubiquitous torque teno virus (TTV) is associated with
immunosuppression in solid organ transplant recipients. Studies in kidney transplant …

Quantification of torque teno virus viremia as a prospective biomarker for infectious disease in kidney allograft recipients

R Strassl, M Schiemann, K Doberer… - The Journal of …, 2018 - academic.oup.com
Background Drug-induced immunosuppression following kidney transplantation is crucial to
prevent allograft rejection, but increases risk for infectious disease. Tailoring of drug dosing …

[HTML][HTML] Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation

O Rezahosseini, CH Drabe, SS Sørensen… - Transplantation …, 2019 - Elsevier
Solid organ transplantation (SOT) recipients receive immunosuppressive therapy to avoid
rejection of the transplanted organ. Immunosuppressive therapy increases the risk of …

Understanding torquetenovirus (TTV) as an immune marker

EJ Gore, L Gard, HGM Niesters… - Frontiers in …, 2023 - frontiersin.org
Torquetenovirus (TTV), a small, single stranded anellovirus, is currently being explored as a
marker of immunocompetence in patients with immunological impairment and inflammatory …

[HTML][HTML] Monitoring of alphatorquevirus DNA levels for the prediction of immunosuppression-related complications after kidney transplantation

M Fernández-Ruiz, E Albert, E Giménez… - American Journal of …, 2019 - Elsevier
The replication kinetics of nonpathogenic anelloviruses belonging to the Alphatorquevirus
genus (such as torque teno virus) might reflect the overall state of posttransplant …

Early post-transplant torquetenovirus viremia predicts cytomegalovirus reactivations in solid organ transplant recipients

F Maggi, D Focosi, M Statzu, G Bianco, C Costa… - Scientific reports, 2018 - nature.com
Monitoring the human virome has been recently suggested as a promising and novel area of
research for identifying new biomarkers which would help physicians in the management of …

Torque teno virus as a novel biomarker targeting the efficacy of immunosuppression after lung transplantation

P Jaksch, M Kundi, I Görzer, G Muraközy… - The Journal of …, 2018 - academic.oup.com
Torque teno viruses (TTV) are small DNA-viruses, of the genus Alphatorquevirus, whose
replication is linked to immune status. TTV load may be an indicator for efficacy of IS in lung …