Effects of clinical, comorbid, and social determinants of health on brain ageing in people with and without HIV: a retrospective case-control study

KJ Petersen, T Lu, J Wisch, J Roman, N Metcalf… - The Lancet …, 2023 - thelancet.com
Background Neuroimaging reveals structural brain changes linked with HIV infection and
related neurocognitive disorders; however, group-level comparisons between people with …

Age-accelerated increase of white matter hyperintensity volumes is exacerbated by heavy alcohol use in people living with HIV

A Pfefferbaum, Q Zhao, KM Pohl, SA Sassoon… - Biological …, 2024 - Elsevier
Background Antiretroviral treatment has enabled people living with HIV infection to have a
near-normal life span. With longevity comes opportunities for engaging in risky behavior …

Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study

PR Millar, BA Gordon, PH Luckett, TLS Benzinger… - Elife, 2023 - elifesciences.org
Background: Estimates of 'brain-predicted age'quantify apparent brain age compared to
normative trajectories of neuroimaging features. The brain age gap (BAG) between …

Plasma Aβ42/Aβ40 ratios in older people with Human Immunodeficiency Virus

SA Cooley, B Nelson, A Boerwinkle… - Clinical Infectious …, 2023 - academic.oup.com
Background As people with human immunodeficiency virus (HIV)(PWH) age, it remains
unclear whether they are at higher risk for age-related neurodegenerative disorders—for …

Brain age as a biomarker for pathological versus healthy ageing–a REMEMBER study

MMJ Wittens, S Denissen, DM Sima, E Fransen… - Alzheimer's Research & …, 2024 - Springer
Objectives This study aimed to evaluate the potential clinical value of a new brain age
prediction model as a single interpretable variable representing the condition of our brain …

Does Maternal HIV Infection Affect Neonatal Outcomes?

M Zarkesh, F Kermani, MB Ghalibaf… - Current HIV …, 2024 - benthamdirect.com
Background Pregnancy among women infected with HIV is classified as a high-risk
pregnancy. While previous research has indicated an elevated likelihood of preterm birth …

[HTML][HTML] Effects of clinical, co-morbid, and social determinants of health on brain aging in persons with and without HIV: a retrospective case-control study

KJ Petersen, T Lu, J Wisch, J Roman, N Metcalf… - The lancet …, 2023 - pmc.ncbi.nlm.nih.gov
Background. Neuroimaging reveals structural brain changes linked with HIV infection and
related neurocognitive disorders; however, group-level comparisons between persons with …

HIV and Early Life Stress on Neuroimaging and Risky Behavior

P Garcia Egan - 2022 - irl.umsl.edu
This study examined the interactive effects of early life stress (ELS) and HIV on brain
morphometry, diffusion-basis-spectrum-imaging (DBSI), risky decision-making, and sex-risk …

Contributions of cerebral white matter hyperintensities, age, and pedal perception to postural sway in people living with HIV

EV Sullivan, NM Zahr, Q Zhao, KM Pohl, SA Sassoon… - AIDS, 2022 - journals.lww.com
Objective: With aging, people living with HIV (PLWH) have diminishing postural stability that
increases liability for falls. Factors and neuromechanisms contributing to instability are …

Functional and Structural Brain Imaging Evidence of Frontostriatal Alterations in HIV and Aging

S Hassanzadeh-Behbahani - 2023 - search.proquest.com
Over 38 million people are living with human immunodeficiency virus (HIV) worldwide.
Although advances in medical treatments have converted HIV from a fatal disease to a …