More than half a century ago researchers thought that d-amino acids had a minor function
compared to l-enantiomers in biological processes. Many evidences have shown that d …

Sodium benzoate and potassium sorbate are extremely useful agents for food and beverage
preservation, yet concerns remain over their complete safety. Benzoate can react with the …

Schizophrenia is a complex and multifactorial disorder generally diagnosed in young adults
at the time of the first psychotic episode of delusions and hallucinations. These positive …

Schizophrenia remains one of the most severe medical diseases. Current dopamine
modulating first-generation and second-generation antipsychotics target mainly positive …

Peroxisomes contain numerous enzymatic activities that are important for mammalian
physiology. Patients lacking either all peroxisomal functions or a single enzyme or …

D-Serine is a potent co-agonist at the NMDA glutamate receptor and has been the object of
many preclinical studies to ascertain the nature of its metabolism, its regional and cellular …

d-amino acids have been detected in a variety of peptides synthesized by animal cells.
These include opiate and antimicrobial peptides from amphibian skin, neuropeptides from …

NMDA Receptors (NMDARs) play key roles in synaptic physiology and NMDAR
hypofunction has been implicated in various neurological conditions. In recent years an …

Background Schizophrenia is a disabling disorder that profoundly affects functioning and
quality of life. While available antipsychotics have improved outcomes for patients with …

Introduction: Abnormalities in glutamatergic neurotransmission mediated by N-methyl-d-
aspartate (NMDA) are implicated in the pathophysiology of schizophrenia, although the …