Bacterial efflux pump OMPs as vaccine candidates against multidrug-resistant Gram-negative bacteria

TO Silva, ACS Bulla, BA Teixeira… - Journal of Leukocyte …, 2024 - academic.oup.com
The emergence and propagation of bacteria resistant to antimicrobial drugs is a serious
public health threat worldwide. The current antibacterial arsenal is becoming obsolete, and …

In Silico Prediction of a Multitope Vaccine against Moraxella catarrhalis: Reverse Vaccinology and Immunoinformatics

MA Soltan, N Elbassiouny, H Gamal, EB Elkaeed… - Vaccines, 2021 - mdpi.com
Moraxella catarrhalis (M. catarrhalis) is a Gram-negative bacterium that can cause serious
respiratory tract infections and middle ear infections in children and adults. M. catarrhalis …

Identification of Antigenic Properties of Acinetobacter baumannii Proteins as Novel Putative Vaccine Candidates Using Reverse Vaccinology Approach

T Piri-Gharaghie, A Doosti, SA Mirzaei - Applied Biochemistry and …, 2022 - Springer
Multidrug-resistant Acinetobacter baumannii (A. baumannii) infections are becoming more
prevalent all over the world. As a cost-effective and preventative method, vaccination seems …

[HTML][HTML] An integrated in silico based subtractive genomics and reverse vaccinology approach for the identification of novel vaccine candidate and chimeric vaccine …

K Khan, K Jalal, R Uddin - Genomics, 2022 - Elsevier
Salmonella typhi is notorious for causing enteric fever which is also known as typhoid fever.
It emerged as an extreme drug resistant strain that requires urgent attention to prevent its …

Recent Progress in Shigella and Burkholderia pseudomallei Vaccines

I Chapartegui-González, S Bowser, AG Torres… - Pathogens, 2021 - mdpi.com
Significant advancement has been made in the development of vaccines against bacterial
pathogens. However, several roadblocks have been found during the evaluation of vaccines …

In silico Designing of an Epitope-Based Vaccine Against Common E. coli Pathotypes

MA Soltan, MY Behairy, MS Abdelkader… - Frontiers in …, 2022 - frontiersin.org
Escherichia coli (E. coli) is a Gram-negative bacterium that belongs to the family
Enterobacteriaceae. While E. coli can stay as an innocuous resident in the digestive tract, it …

Identification and evaluation of novel vaccine candidates against Shigella flexneri through reverse vaccinology approach

A Hajialibeigi, J Amani, SLM Gargari - Applied Microbiology and …, 2021 - Springer
Shigellosis is a significant type of diarrhea that causes 160,000 deaths annually in a global
scale. The mortality occurs mainly in children less than 5 years of age. No licensed vaccine …

Expression and purification of TolC as a recombinant protein vaccine against Shigella flexneri and evaluation of immunogenic response in mice

R Veisi, S Nazarian, J Fathi, N Hadi - Microbial Pathogenesis, 2024 - Elsevier
Background Shigella is one of the major causes of dysenteric diarrhea, which is known
shigelosis. Shigelosis causes 160,000 deaths annually of diarrheal disease in the global …

Computational exploration and design of a multi-epitopes vaccine construct against Chlamydia psittaci

AM Alsubaiyel, SI Bukhari - Journal of Biomolecular Structure and …, 2024 - Taylor & Francis
Chlamydia psittaci is an intracellular pathogen and causes variety of deadly infections in
humans. Antibiotics are effective against C. psittaci however high percentage of resistant …

Identification of novel vaccine candidates in the whole-cell Aeromonas hydrophila biofilm vaccine through reverse vaccinology approach

B Kaur, BTN Kumar, A Tyagi, SA Holeyappa… - Fish & Shellfish …, 2021 - Elsevier
Biofilm vaccine has been recognised as one of the successful strategy to reduce the
Aeromonas hydrophila infection in fish. But, the vaccine contains the protective and non …