This review presents a practical summary of the missing data literature, including a sketch of
missing data theory and descriptions of normal-model multiple imputation (MI) and …

Randomized clinical trials are the primary tool for evaluating new medical interventions.
Randomization provides for a fair comparison between treatment and control groups …

Objective: The premise of the National Institute of Mental Health Recovery After an Initial
Schizophrenia Episode Early Treatment Program (RAISE-ETP) is to combine state-of-the-art …

Background Participation in work and school are central objectives for first episode
psychosis (FEP) programs, but evidence effectiveness has been mixed in studies not …

Abstract Intention‐to‐treat (ITT) in randomized controlled trials involves keeping participants
in the treatment groups to which they were randomized regardless of whether they withdraw …

Background: Bipolar disorder is among the 10 most disabling medical conditions worldwide.
While lithium has been used extensively for bipolar disorder since the 1970s, second …

Objective Lithium salts, once the mainstay of therapy for bipolar disorder, have tolerability
issues at a higher dosage that often limit adherence. The authors investigated the …

This article summarizes recommendations on the design and conduct of clinical trials of a
National Research Council study on missing data in clinical trials. Key findings of the study …

Objective: Despite treatment advances in other domains, inpatient psychiatric hospitalization
rates for individuals with first-episode psychosis remain high. Even with early intervention …

Background: Psychotherapy noncompletion rates for veterans and their families are high.
This study sought to (a) measure noncompletion rates of such patients at a university-based …