Acute chest syndrome (ACS) is a frequent cause of acute lung disease in children with sickle
cell disease (SCD). Patients may present with ACS or may develop this complication during …

Acute chest syndrome (ACS) is a common complication and reason for hospital admission in
patients with sickle cell disease (SCD). It is also the most common cause of death in this …

1Department of Haematology, Guy's and St Thomas' NHS Foundation Trust, 2Lane Fox
Respiratory Unit, St Thomas' Hospital, Guy's and St Thomas' NHS Foundation Trust …

Introduction Sickle cell disease, one of the world's most prevalent Mendelian disorders, is a
chronic hemolytic anemia punctuated by acute vasoocclusive events. Both hemolysis and …

Hypoxemia is common in SCD and likely exacerbates SCD vasculopathy. Pulse oximeter
correlation with arterial oxygen tension in patients with SCD may at times be poor and …

Rationale: Sickle cell disease (SCD) results in significant morbidity and mortality attributable
to pulmonary complications. The pattern of lung function change across childhood in SCD is …

Objectives To prospectively assess longitudinal lung function in children with sickle cell
disease (SCD). Working hypothesis Lung function in SCD children deteriorates with …

Introduction Acute chest syndrome (ACS) in sickle cell disease (SCD) is a serious condition
that carries with it a high rate of morbidity and mortality. Objective This review highlights the …

Objectives: The aim of this study was to evaluate the existing newborn sickle
haemoglobinopathy screening programme in Jamaica. Methods: A retrospective analysis of …

A physician diagnosis of asthma in children and adults with sickle cell disease (SCD) has
been associated with increased rates of pain and acute chest syndrome (ACS) episodes …