Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Oxidative stress (OS), a state characterized by an imbalance between pro-oxidant molecules
including reactive oxygen and nitrogen species, and antioxidant defenses, has been …

More than 135 million births occur each year; yet, the molecular underpinnings of human
parturition in gestational tissues, and in particular the placenta, are still poorly understood …

Problem Inflammation and infection play a major role in preterm birth. The purpose of this
study was to (i) determine the prevalence and clinical significance of sterile intra‐amniotic …

Pregnancy is a unique immunological state in which a balance of immune tolerance and
suppression is needed to protect the fetus without compromising the mother. It has long …

Objective To determine the frequency and type of histopathologic lesions in placentas
delivered by women with a normal pregnancy outcome. Methods This retrospective cohort …

The elaboration of cytokines, chemokines and immunomodulatory proteins in the placenta
and gestational membranes has been extensively investigated in the context of both normal …

Oxidative stress (OS), which arises through an imbalance between the formation of reactive
oxygen species (ROS) and antioxidant defenses, plays a key role in the pathophysiology of …

Parturition is a well-orchestrated process characterized by increased uterine contractility,
cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a …

Preterm birth is associated with high rates of infant mortality and morbidity. This review
emphasizes that the onset of labor entails a molecular collaboration between the mother …