[HTML][HTML] Protective role of melatonin and its metabolites in skin aging

G Bocheva, RM Slominski, Z Janjetovic, TK Kim… - International journal of …, 2022 - mdpi.com
The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …

Melatonin as an antioxidant and immunomodulator in atopic dermatitis—A new look on an old story: A Review

AK Jaworek, JC Szepietowski, P Hałubiec… - Antioxidants, 2021 - mdpi.com
Atopic dermatitis (AD) is common inflammatory dermatosis, typically with chronic and
recurrent course, which significantly reduces the quality of life. Sleep disturbances are …

Melatonin promotes male reproductive performance and increases testosterone synthesis in mammalian Leydig cells

M Yang, S Guan, J Tao, K Zhu, D Lv… - Biology of …, 2021 - academic.oup.com
Leydig cells play a critical role in male reproductive physiology, and their dysfunction is
usually associated with male infertility. Melatonin has an important protective and regulatory …

Pan‐Cancer analyses reveal Genomics and clinical characteristics of the Melatonergic regulators in cancer

J Zhang, H Jiang, K Du, T Xie, B Wang… - Journal of pineal …, 2021 - Wiley Online Library
Melatonin, an endogenous hormone, plays protective roles in cancer. In addition to
regulating circadian rhythms, sleep, and neuroendocrine activity, melatonin functions in …

Melatonin promotes progesterone secretion in sheep luteal cells by regulating autophagy via the AMPK/mTOR pathway

H Duan, S Yang, L Xiao, S Yang, Z Yan, F Wang, X Ma… - Theriogenology, 2024 - Elsevier
The corpus luteum is primarily responsible for the production and secretion of progesterone.
Melatonin has been established to regulate autophagy and induce progesterone secretion …

Melatonin as a multifunctional modulator: emerging insights into its role in health, reproductive efficiency, and productive performance in livestock

A Afzal - Frontiers in physiology, 2024 - frontiersin.org
Melatonin, a pleiotropic hormone plays a vital role in enhancing livestock performance not
only by regulating circadian rhythms but also by exhibiting antioxidant, immunomodulatory …

Melatonin facilitates oocyte growth in goats and mice through increased nutrient reserves and enhanced mitochondrial function

C He, H Wu, R Liu, J Liao, X Wang, H Shi… - The FASEB …, 2024 - Wiley Online Library
Oogenesis involves two phases: initial volumetric growth driven by nutrient accumulation
and subsequent nuclear maturation. While melatonin (MLT) has been employed as a …

Role of Melatonin in Ovarian Function

G Basini, F Grasselli - Animals, 2024 - mdpi.com
Simple Summary Melatonin is a hormone known for regulating the sleep–wake cycle and as
an indicator of the photoperiod in seasonally reproducing mammals. Its direct role in ovarian …

A mathematical model of melatonin synthesis and interactions with the circadian clock

J Best, R Kim, M Reed, HF Nijhout - Mathematical Biosciences, 2024 - Elsevier
A new mathematical model of melatonin synthesis in pineal cells is created and connected
to a slightly modified previously created model of the circadian clock in the suprachiasmatic …

Effects of melatonin supplementation during pregnancy on reproductive performance, maternal–placental–fetal redox status, and placental mitochondrial function in a …

X Peng, X Cai, J Li, Y Huang, H Liu, J He, Z Fang… - Antioxidants, 2021 - mdpi.com
Melatonin (MT) is a bio-antioxidant that has been widely used to prevent pregnancy
complications, such as pre-eclampsia and IUGR during gestation. This experiment …