Most human diseases have underlying genetic causes. To better understand the impact of
genes on disease and its implications for medicine and public health, researchers have …

Replication, validation and extension of experiments are crucial for scientific progress.
Computational experiments are scriptable and should be easy to reproduce. However …

Cytogenetics has long represented a critical component in the clinical evaluation of
hematologic malignancies. Chromosome banding studies provide a simultaneous snapshot …

In the context of solid tumours, the evolution of cancer therapies to more targeted and
nuanced approaches has led to the impetus for personalised medicine. The targets for these …

Due to the current high availability of omics, data-driven biology has greatly expanded, and
several papers have reviewed state-of-the-art technologies. Nowadays, two main types of …

Biomedical innovation and translation are increasingly emphasizing research using “big
data.” The hope is that big data methods will both speed up research and make its results …

Background/Aim: Malignant mesothelioma is a rare malignancy with limited therapeutic
options. Exome-based next-generation sequencing (NGS) techniques may direct the future …

Background While next-generation sequencing (NGS) costs have fallen in recent years, the
cost and complexity of computation remain substantial obstacles to the use of NGS in bio …

Main conclusion High-quality and dense genetic maps were constructed, and leaf shape
variation was dissected by QTL mapping in poplar. Species in the genus Populus, also …

Extremely low coverage whole genome sequencing (lcWGS) is an economical technique to
obtain high-density single nucleotide polymorphisms (SNPs). Here, we explored the …