Identification of therapeutic targets for Alzheimer's Disease Treatment using bioinformatics and machine learning
ZQ Xie, YL Situ, L Deng, M Liang, H Ding, Z Guo… - Scientific Reports, 2025 - nature.com
Alzheimer's disease (AD) is a complex neurodegenerative disorder that currently lacks
effective treatment options. This study aimed to identify potential therapeutic targets for the …
effective treatment options. This study aimed to identify potential therapeutic targets for the …
[HTML][HTML] Butyrate Prevents Obesity Accompanied by HDAC9-Mediated Browning of White Adipose Tissue
J Yang, G Li, S Wang, M He, S Dong, T Wang, B Shi… - Biomedicines, 2025 - mdpi.com
Background/Objectives: Mounting evidence indicates that the short-chain fatty acid butyrate
protects against obesity and associated comorbidities, partially through the induction of …
protects against obesity and associated comorbidities, partially through the induction of …
Efficient multi-phenotype genome-wide analysis identifies genetic associations for unsupervised deep-learning-derived high-dimensional brain imaging phenotypes
Brain imaging is a high-content modality that offers dense insights into the structure and
pathology of the brain. Existing genetic association studies of brain imaging, typically …
pathology of the brain. Existing genetic association studies of brain imaging, typically …
Dynamic regulation of mRNA acetylation at synapses by learning and memory
H zhou, J zhang, Z Zhu, WP Lin, YY Ding, FY Dai… - bioRxiv, 2024 - biorxiv.org
N4-acetylcytidine (ac4C) is the only RNA acetylation modification identified in eukaryotes
and has recently been recognized as an epitranscriptomic mechanism regulating mRNA …
and has recently been recognized as an epitranscriptomic mechanism regulating mRNA …