The endolysosomal system in conventional and unconventional protein secretion

E Néel, M Chiritoiu-Butnaru, W Fargues… - Journal of Cell …, 2024 - rupress.org
Most secreted proteins are transported through the “conventional” endoplasmic reticulum–
Golgi apparatus exocytic route for their delivery to the cell surface and release into the …

Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non‐inducing cancer cells

SV Chitti, T Kang, P Fonseka, AL Marzan… - …, 2023 - Wiley Online Library
Cancer cachexia is a wasting syndrome characterised by the loss of fat and/or muscle mass
in advanced cancer patients. It has been well‐established that cancer cells themselves can …

Emerging concepts of myosin 18A isoform mechanobiology in organismal and immune system physiology, development, and function

W DeKryger, ZC Chroneos - The FASEB Journal, 2024 - Wiley Online Library
Alternative and combinatorial splicing of myosin 18A (MYO18A) gene transcripts results in
expression of MYO18A protein isoforms and isoform variants with different membrane and …

The potential role of liquid–liquid phase separation in the cellular fate of the compartments for unconventional protein secretion

LFS Mendes, CO Gimenes, MDO da Silva… - Protein …, 2024 - Wiley Online Library
Eukaryotic cells have developed intricate mechanisms for biomolecule transport, particularly
in stressful conditions. This interdisciplinary study delves into unconventional protein …

Sécrétion non conventionnelle-Nouvelles perspectives dans le trafic des protéines

M Denus, W Fargues, A Filaquier, É Néel… - médecine …, 2024 - medecinesciences.org
L'étude de l'organisation structurale et fonctionnelle des cellules eucaryotes a révélé les
compartiments membranaires ainsi que la machinerie nécessaires au trafic vésiculaire des …