Abstract Matrix metalloproteinase-7 (MMP-7) is a small proteolytic enzyme that secretes zinc
and calcium endopeptidases. It can degrade a variety of extracellular matrix substrates and …

Simple Summary Colorectal cancer (CRC) is one of the most common cancer worldwide.
CRC is derived from polyps and many factors, such as Matrix Metalloproteinases (MMPs) …

Abstract Background Matrixmetalloproteinases (MMPs) comprise a family of zinc-dependent
endopeptidases which are involved in angiogenesis, tumor invasion and metastatic …

Epithelial to mesenchymal transition (EMT), invasion, and motility are essential steps in
colorectal cancer (CRC) metastasis regulated by HIF‐1α and NF‐κB. Since HSP90 activates …

Matrix metallopeptidase 3 or MMP3, is a zinc-dependent proteolytic enzyme that is involved
in various physiological processes via modification of the extracellular matrix. In particular …

Objective: Tissue inhibitor of metalloproteinases 1 (TIMP-1) and matrix metalloproteinase 7
(MMP-7) were reported to have potent growth promoting activity. Lack of balance between …

The serum levels and activity of matrix metalloproteinases (MMPs) are associated with the
risk of coronary artery calcification (CAC). We sought to investigate the association between …

Chronic myeloproliferative disorders such as polycythemia vera (PV), essential
thrombocytosis (ET), and idiopathic myelofibrosis arise from clonal proliferation of neoplastic …

Introduction Levels of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs)
influence recombinant tissue plasminogen activator (rtPA) therapy response in patients with …

BACKGROUND MMP-2 also known as gelatinase A and MMP-7 (matrilysin) are members of
the zinc-dependent family of MMPs (Matrix metalloproteinase). MMP-2 and MMP-7 are …