Malaria poses a severe public health risk and a significant economic burden in disease-
endemic countries. One of the most severe issues in malaria control is the development of …

One of the most sought-after therapeutic targets for treating human cancers is the
phosphoinositide 3-kinase; PI3k is an integral part of the PI3K/protein kinase B signaling …

After lung cancer, which is the most common cancer overall, breast cancer is the second
most common cancer in women. Breast cancer is primarily brought on by 17-estradiol, a key …

Pyrazole core represents a privilege scaffold in medicinal chemistry; a number of pyrazole
compounds are endowed with various pharmacological activities in different therapeutic …

A series of oxadiazole-based five-membered heterocyclic derivatives was designed and
synthesized with the intent of exclusive cyclo-oxygenase-2 (COX-2) inhibition to acquire anti …

This article provides a basic summary of computational research on benzimidazole and its
molecular targets in breast cancer (BC) drug discovery. The drug development process is …

To combat resistance against current antimalarials, modifying key pharmacophores and
exploring novel parasite-specific drug targets remained one of the key drug design …

Breast cancer is globally associated with majority of the women. Indeed, high estrogen
levels are the most common subtype of breast cancer. Three different classes of estrogen …

The most prevalent malignancy among women is breast cancer, which had almost 1.3
million new cases in 2020. It is the second most common cancer in the world, followed by …

This article provides some basic summary of computational research on benzimidazole and
its molecular targets in breast cancer (BC) drug discovery and the drug development …