Lutein and zeaxanthin (L/Z) are the predominant carotenoids which accumulate in the retina
of the eye. The impact of L/Z intake on the risk and progression of age-related macular …

Current evidence suggests lutein and its isomers play important roles in ocular development
in utero and throughout the life span, in vision performance in young and later adulthood …

Lutein is one of the few xanthophyll carotenoids that is found in high concentration in the
macula of human retina. As de novo synthesis of lutein within the human body is impossible …

Nutraceuticals have gained increasing attention over the last years due to their potential
value as therapeutic compounds formulated from natural sources. For instance, there is a …

Oxidative stress is one of the common factors leading to age‐related eye diseases in older
adults. Factors such as high oxygen consumption, high concentration of polyunsaturated …

Damage to the retinal pigment epithelium, Bruch's membrane and/or tissues underlying
macula is known to increase the risk of age-related macular degeneration (AMD). AMD is …

Cosmos caudatus or Ulam Raja in Malay originated from Latin America and transferred to
Europe, Africa, and tropical Asia. It has been known for many traditional practices worldwide …

Lutein is widely used as diet supplement for prevention of age-related macular
degeneration. However, the application and efficacy of lutein in food and nutritional products …

Obesity is characterized by the rapid expansion of visceral adipose tissue, resulting in a
hypoxic environment in adipose tissue which leads to a profound change of gene …

The antioxidant and anti-inflammatory effects of carotenoid have been determined to aid in
the prevention of a wide range of oxidative disorders, arteriosclerosis, obesity, and various …