Bioluminescence is the fascinating natural phenomenon by which living creatures produce
light. Bioluminescence occurs when the oxidation of a small-molecule luciferin is catalysed …

DNA nanotechnology has now enabled the self-assembly of almost any prescribed 3-
dimensional nanoscale structure in large numbers and with high fidelity. These structures …

Bioluminescence methodologies have been extraordinarily useful due to their high
sensitivity, broad dynamic range, and operational simplicity. These capabilities have been …

Dynamic interactions between proteins comprise a key mechanism for temporal control of
cellular function and thus hold promise for development of novel drug therapies. It remains …

in vivo bioluminescence imaging (BLi) is an optical molecular imaging technique used to
visualize molecular and cellular processes in health and diseases and to follow the fate of …

Luminescence imaging has gained attention as a promising bio-imaging modality in
situations where fluorescence imaging cannot be applied. However, wider application to …

Bioluminescence imaging (BLI) using luciferase reporters is an indispensable method for
the noninvasive visualization of cell populations and biochemical events in living animals …

Although fluorescent reporters and biosensors have become indispensable tools in
biological and biomedical fields, fluorescence measurements require external excitation …

Fluorescence and bioluminescence resonance energy transfer (FRET and BRET)
techniques allow the sensitive monitoring of distances between two labels at the nanometer …

Fluorescence has long been recognized as a powerful tool for probing biological structure
and function. Nearly sixty-five years ago, Coons and colleagues introduced the first …