Antifungal drugs: New insights in research & development

AM Nicola, P Albuquerque, HC Paes… - Pharmacology & …, 2019 - Elsevier
The need for better antifungal therapy is commonly accepted in view of the high mortality
rates associated with systemic infections, the low number of available antifungal classes …

New and promising chemotherapeutics for emerging infections involving drug-resistant non-albicans Candida species

LN Silva, TP de Mello… - Current Topics in …, 2019 - ingentaconnect.com
Fungal infections are a veritable public health problem worldwide. The increasing number of
patient populations at risk (eg transplanted individuals, cancer patients, and HIV-infected …

Zinc (II) complexes bearing N, N, S ligands: Synthesis, crystal structure, spectroscopic analysis, molecular docking and biological investigations about its antifungal …

RAC Souza, VL Cunha, JH de Souza… - Journal of Inorganic …, 2022 - Elsevier
In the present work, the synthesis, characterization, antifungal activity, molecular docking
study and in silico approach of five thiosemicarbazone derivatives and their corresponding …

Synthesis, antifungal evaluation, and molecular docking studies of steroidal thiazolopyrimidines

A Iqbal, A Khan, S Ahmedi, N Manzoor, T Siddiqui - Steroids, 2023 - Elsevier
A series of steroidal thiazolopyrimidine derivatives were developed and evaluated for their
antifungal properties against Candida species using steroid as the basic skeleton and a …

Cyanopropyl functionalized benzimidazolium salts and their silver N‐heterocyclic carbene complexes: Synthesis, antimicrobial activity, and theoretical analysis

D Türker, E Üstün, S Günal, H Yıldız… - Archiv der …, 2022 - Wiley Online Library
The reaction of N‐substituted benzimidazole with 4‐bromobutyronitrile gives the
corresponding benzimidazolium salts as N‐heterocyclic carbene (NHC) precursors. Silver (I) …

Anti-Candida albicans Activity of Ononin and Other Secondary Metabolites from Platonia Insignis MART

AF Silva, JR Farias, DCG Franco, AA Galiza, EP Motta… - Metabolites, 2022 - mdpi.com
Candida albicans is a human pathogen that is part of the healthy microbiome. However, it is
often associated with opportunistic fungal infections. The treatment of these infections is …

Synthesis, characterization, reaction mechanism prediction and biological study of mono, bis and tetrakis pyrazole derivatives against Fusarium oxysporum f. sp …

Y Kaddouri, F Abrigach, S Ouahhoud, R Benabbes… - Bioorganic …, 2021 - Elsevier
Twelve heterocyclic compounds were prepared using the condensation of hydroxymethanol
pyrazole derivatives with different primary aminesas example 2-aminothiazole and 1 …

Network pharmacology and experimental assessment to explore the pharmacological mechanism of Qimai Feiluoping decoction against pulmonary fibrosis

Y Yang, L Ding, T Bao, Y Li, J Ma, Q Li, Z Gao… - Frontiers in …, 2021 - frontiersin.org
Pulmonary fibrosis (PF) is one of the pathologic changes in COVID-19 patients in
convalescence, and it is also a potential long-term sequela in severe COVID-19 patients …

Targeted specific inhibition of bacterial and Candida species by mesoporous Ag/Sn–SnO 2 composite nanoparticles: In silico and in vitro investigation

M Pandey, K Wasnik, S Gupta, M Singh, S Patra… - RSC …, 2022 - pubs.rsc.org
Invasive bacterial and fungal infections have notably increased the burden on the health
care system and especially in immune compromised patients. These invasive bacterial and …

[HTML][HTML] Design, Synthesis, Molecular Docking, and ADME-Tox Investigations of Imidazo [1, 2-a] Pyrimidines Derivatives as Antimicrobial Agents

D Benzenine, I Daoud, N Aissaoui, Z Kibou, JA Seijas… - Molecules, 2024 - mdpi.com
A convenient and effective synthesis of imidazo [1, 2-a] pyrimidine derivatives has been
developed under microwave irradiations using Al2O3 as a catalyst in solvent-free …