The translation of messenger RNA (mRNA) into protein and the folding of the resulting
protein into an active form are prerequisites for virtually every cellular process and represent …

Translation is a crucial step in gene expression and plays a vital role in regulating various
aspects of plant development and environmental responses. It is a dynamic and complex …

In animal oocytes and early embryos, mRNA poly (A)-tail length strongly influences
translational efficiency (TE), but later in development this coupling between tail length and …

Control of insulin mRNA translation is crucial for energy homeostasis, but the mechanisms
remain largely unknown. We discovered that insulin mRNAs across invertebrates …

Neurons exhibit a striking degree of functional diversity, each one tuned to the needs of the
circuitry in which it is embedded. A fundamental functional dichotomy occurs in activity …

Upstream open reading frames (uORFs) play important roles in regulating the main coding
DNA sequences (CDSs) via translational repression. Despite their prevalence in the …

Neoplastic cells need to adapt their gene expression pattern to survive in an ever-changing
or unfavorable tumor microenvironment. Protein synthesis (or mRNA translation), an …

Synaptic terminals grow and retract throughout life, yet synaptic strength is maintained within
stable physiological ranges. To study this process, we investigated Drosophila endophilin …

Presynaptic homeostatic plasticity (PHP) adaptively enhances neurotransmitter release
following diminished postsynaptic glutamate receptor (GluR) functionality to maintain …

Stem cells in many systems, including Drosophila germline stem cells (GSCs), increase
ribosome biogenesis and translation during terminal differentiation. Here, we show that the …