Lipid metabolism has been increasingly recognized to play an influencing role in tumor
initiation, progression, metastasis, and therapeutic drug resistance. Targeting lipid metabolic …

Ferroptosis-mediated multimodal therapy has emerged as a promising strategy for tumor
elimination, with lipid peroxide (LPO) playing a pivotal role. However, the therapeutic …

Lipophagy is defined as the autophagic degradation of lipid droplets. It is a selective
autophagy process that can continuously circulate and redistribute metabolites to maintain …

Background Bufalin (BA) is a potent traditional Chinese medicine derived from toad venom.
It has shown significant antitumor activity, but its use is limited by cardiotoxicity, which …

Autophagy-mediated anoikis resistance plays a critical role in the initiation of tumor
metastasis. Therefore, we investigated the role and mechanism of anoikis resistance …

Epilepsy is a common neurological condition characterized by abnormal neuronal activity,
often leading to cellular damage and death. There is evidence to suggest that lipid …

The effects of Enterococcus faecalis (E. faecalis) at a concentration of 1.0× 108 CFU/mL on
growth performance, hepatic lipid metabolism, and mRNA expression related to lipid …

Abstract Objective: Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1)
encodes a core protein that has a crucial function in the metabolism of cholesterol and lipids …

KAP1 controls cell fate specification of spermatogonial, skeletal, and hematopoietic
progenitors, and promotes embryonic and breast cancer stem cell renewal. It regulates cell …

Cholesterol metabolism plays a vital role in tumor proliferation, regulation of tumor immune
escape, and drug resistance. This study aimed to investigate the predictive value of …