Oxidation chemistry using enzymes is approaching maturity and practical applicability in
organic synthesis. Oxidoreductases (enzymes catalysing redox reactions) enable chemists …

Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

Sustainable or green chemistry has established firm ground providing essential design
criteria for the development of efficient chemical syntheses of complex, high added value …

Multicomponent reactions have become increasingly popular as tools for the rapid
generation of small‐molecule libraries. However, to ensure sufficient molecular diversity and …

Multicomponent reactions (MCRs) receive increasing attention because they address both
diversity and complexity in organic synthesis. Thus, in principle diverse sets of relatively …

A domino reaction has been defined by Tietze as a reaction involving two or more bond-
forming transformations that take place under the same reaction conditions, without adding …

Enzyme catalysis is gaining increasing importance in synthetic chemistry. Nowadays, the
growing number of biocatalysts accessible by means of bioinformatics and enzyme …

Multicomponent reactions are flexible reactions for the rapid generation of complex
molecules with often biologically relevant scaffold structures. Combined with the ease of …

Multicomponent reactions have gained significant importance as a tool for the synthesis of a
wide variety of useful compounds, including pharmaceuticals. In this context, the multiple …

The ongoing trends to process improvements, cost reductions and increasing quality, safety,
health and environment requirements of industrial chemical transformations have …