A rapid and stable spontaneous reprogramming system of Spermatogonial stem cells to Pluripotent State
R Wei, X Zhang, X Li, J Wen, H Liu, J Fu, L Li… - Cell & Bioscience, 2023 - Springer
Background The scarcity of pluripotent stem cells poses a major challenge to the clinical
application, given ethical and biosafety considerations. While germline stem cells commit to …
application, given ethical and biosafety considerations. While germline stem cells commit to …
BMI1 fine-tunes gene repression and activation to safeguard undifferentiated spermatogonia fate
R Liu, Y Peng, W Du, Y Wu, W Zhang, C Hu… - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Spermatogenesis is sustained by the homeostasis of self-renewal and
differentiation of undifferentiated spermatogonia throughout life, which is regulated by …
differentiation of undifferentiated spermatogonia throughout life, which is regulated by …
Low dose of zearalenone inhibited the proliferation of porcine prospermatogonia and transformed the physiology through cytokine-cytokine receptor interaction
J Wang, H Tian, H Liu, J Wen, R Huang, K Zou, L Hou… - Theriogenology, 2023 - Elsevier
Zearalenone (ZEA) is a prevalent mycotoxin functions as an endocrine disrupter to the
reproductive systems of farm animals, especially in pigs. To evaluate the effect and the …
reproductive systems of farm animals, especially in pigs. To evaluate the effect and the …
Expression profiling of stemness markers in testicular germline stem cells from neonatal and adult Swiss albino mice during their transdifferentiation in vitro
S Indu, AN Devi, M Sahadevan, J Sengottaiyan… - Stem Cell Research & …, 2024 - Springer
Abstract Background Spermatogonial stem cells (SSCs) were considered to be stem cells
with limited potencies due to their existence in adult organisms. However, the production of …
with limited potencies due to their existence in adult organisms. However, the production of …
Androgen blockage impairs proliferation and function of Sertoli cells via Wee1 and Lfng
W Zhai, H Tian, X Liang, Y Wu, J Wen, Z Liu… - Cell Communication and …, 2024 - Springer
Background Androgens are essential hormones for testicular development and the
maintenance of male fertility. Environmental factors, stress, aging, and psychological …
maintenance of male fertility. Environmental factors, stress, aging, and psychological …
Regulation of male germline transmission patterns by the Trp53-Cdkn1a pathway
M Kanatsu-Shinohara, H Naoki, T Tanaka, M Tatehana… - Stem Cell Reports, 2022 - cell.com
A small number of offspring are born from the numerous sperm generated from
spermatogonial stem cells (SSCs). However, little is known regarding the rules and …
spermatogonial stem cells (SSCs). However, little is known regarding the rules and …