Malaria comprises a spectrum of disease syndromes and the immune system is a major
participant in malarial disease. This is particularly true in relation to the immune responses …

Our understanding of gut microbial populations and their immense influence on host
immunity, health, and diseases has increased deeply in recent years. Numerous reports …

Background Shifts in dietary patterns during lifestyle transitions are integral components of
the dynamic interactions between humans and their environments. Investigating the link …

Abstract Objectives Fulani in Africa are known to be less susceptible to Plasmodium
falciparum (Pf) malaria. This study explored a potential involvement of antibody-mediated …

Background Genome-wide association studies have identified ATP2B4 as a severe malaria
resistance gene. Recently, 8 potential causal regulatory variants have been shown to be …

Malaria is caused by infection with Plasmodium parasites, which are spread by Anopheles
mosquitoes. In 2022, there were over 600,000 malaria deaths, most in children younger than …

Host responses in Plasmodium falciparum malaria vary between individuals and ethnic
groups through poorly understood mechanisms. In addition to de novo synthesis of essential …

Genomics has provided unprecedented opportunities for understanding the genetic
architecture and evolutionary history of human traits. Unfortunately, human genomics has …

Despite years of research, malaria remains a significant global health burden, with poor
diagnostic tests and increasing antimalarial drug resistance challenging diagnosis and …