Prion diseases are a group of incurable zoonotic neurodegenerative diseases (NDDs) in
humans and other animals caused by the prion proteins. The abnormal folding and …

Lithium is a well-known FDA-approved treatment for bipolar and mood disorders. Lithium
has been an enigmatic drug with multifaceted actions involving various neurotransmitters …

Status epilepticus (SE) refers to a single seizure that lasts longer than typical seizures or a
series of consecutive seizures. The hippocampus, which is vulnerable to the effects of SE …

The lithium-pilocarpine model is commonly used to recapitulate characteristics of human
intractable focal epilepsy. In the current study, we explored the impact of topiramate (TPM) …

Objective Currently, lacosamide (LCM) is not approved for use in status epilepticus (SE) but
several shreds of evidence are available to support its use. The present study was …

The management of bipolar disorder (BD) may be challenging because of the disease state
itself. In addition, the maintenance of the drug level of lithium plays a vital role in preventing …

Prion diseases still remain incurable despite multiple efforts to develop a treatment.
Therefore, it is important to find strategies to at least reduce the symptoms. Lithium has been …

Status epilepticus (SE) is a life-threatening neurological disorder that causes neuronal death
and glial activation. Studies have explained the clinical side effects and lack of effectiveness …

Background and objectives: Epilepsy is a neurological disorder in which the patient suffers
with two or more unprovoked seizures. It is one of the most common neurological disorders …

По данным Всемирной организации здравоохранения, распространенность эпилепсии
в мире высока: заболеваемость населения составляет около 0, 5-1%. В 20-40% случаях …