Myocardial infarction (MI) imposes a huge medical and economic burden on society, and
cardiac repair after MI involves a complex series of processes. Understanding the key …

Congenital heart disease is the most common birth defect worldwide. Defective cardiac
myogenesis is either a major presentation or associated with many types of congenital heart …

Bisphenol A (BPA), present in many household products, can damage the male reproductive
system. Accordingly, we summarized urine samples from 6921 human in National Health …

Myocardial infarction that causes damage to heart muscle can lead to heart failure. The
identification of molecular mechanisms promoting myocardial regeneration represents a …

Zebrafish have a remarkable ability to regenerate injured hearts. Altered hemodynamic
forces after larval ventricle ablation activate the endocardial Klf2a-Notch signaling cascade …

From molecular and cellular perspectives, heart failure is caused by the loss of
cardiomyocytes—the fundamental contractile units of the heart. Because mammalian …

Mutations in ERCC2/XPD helicase, an important component of the TFIIH complex, cause
distinct human genetic disorders which exhibit various pathological features. However, the …

The vertebral column, with the centra as its iteratively arranged building blocks, represents
the anatomical key feature of the vertebrate phylum. In contrast to amniotes, where vertebrae …

Ischemic heart disease (IHD) is the leading cause of heart failure (HF) and is a significant
cause of morbidity and mortality globally. An ischemic event induces cardiomyocyte death …

As the core component of telomeres, the Shelterin complex interacts with telomerase and
the CST complex and plays a crucial role in maintaining telomere structure. Perturbation of …