Abstract Nanocrystals have contributed to exciting improvements in the delivery of poorly
water-soluble drugs. The biological and intracellular fates of nanocrystals are currently …

Nanoencapsulation is an approach to circumvent shortcomings such as reduced
bioavailability, undesirable side effects, frequent dosing and unpleasant organoleptic …

The administration of conventional dosage forms of itraconazole (ITZ) for cutaneous
candidiasis treatment is limited by its poor aqueous solubility and the deep location of …

Drug nanocrystals, which are comprised of active pharmaceutical ingredients and only a
small amount of essential stabilizers, have the ability to improve the solubility, dissolution …

Drug nanocrystals have been used for a wide range of drug delivery platforms in the
pharmaceutical industry, especially for bioavailability enhancement of poorly water-soluble …

Our main aim in the present investigation, development and evaluation of the Niclosamide
(NCL) based nanocrystals (NC) and hydrogel to provide effective anti-psoriatic activity. The …

Currently, numerous new compounds suffer from poor water solubility, hindering their oral
absorption from the gastrointestinal tract and thereby limiting their clinical application …

Dapsone (DAP) is a dual-function drug substance; however, its limited water solubility may
impair its bioavailability. Drug nanocrystals are an alternative to overcome this limitation …

This study investigated the combination of different proportions of cationic chitosan and
anionic carboxymethyl cellulose (CMC) for the development of polyelectrolyte complexes to …

As a major cause of neurodegeneration in the elderly, Parkinson's disease (PD) has
attracted intense research attention. PD results from a decline in the numbers of …