Cellulose derivatives represent a viable alternative to pure cellulose due to their solubility in
water and common organic solvents. This, coupled with their low cost, biocompatibility, and …

For the past two decades, atomic gold nanoclusters (AuNCs, ultrasmall clusters of several to
100 gold atoms, having a total diameter of< 2 nm) have emerged as promising agents in the …

Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible,
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …

The complexity of the tumor microenvironment presents significant challenges to cancer
therapy, while providing opportunities for targeted drug delivery. Using characteristic signals …

Human DNA topoisomerase II is an important target in anticancer therapy. Despite the
clinical success of drugs that target topoisomerase II, the development of resistant cancer …

Undesired physiological instability of nanocarriers and premature drug leakage during
blood circulation result in compromised therapeutic efficacy and severe side effects, which …

In advanced breast cancer (BCa) patients, not the primary tumor, but the development of
distant metastases, which occur mainly in the organ bone, and their adverse health effects …

Stimuli-responsive nanoparticles are focused to promote the pathological specificity and
controlled therapeutic activation in biomedicine, but the multifunctional modulation remains …

The codelivery of drugs at specific optimal ratios to cancer cells is vital for combination
chemotherapy. However, most of the current strategies are unable to coordinate the loading …

Camptothecin (CPT), an alkaloid isolated from the Camptotheca tree, has demonstrated
significant anticancer properties in a range of malignancies. However, its therapeutic …