Oxidases and reactive oxygen species during hematopoiesis: a focus on megakaryocytes

A Eliades, S Matsuura, K Ravid - Journal of cellular physiology, 2012 - Wiley Online Library
Reactive oxygen species (ROS), generated as a result of various reactions, control an array
of cellular processes. The role of ROS during megakaryocyte (MK) development has been a …

Effects of the solid lipid nanoparticle of carvacrol on rodents with lung injury from smoke inhalation

FO Carvalho, ÉR Silva, PS Nunes, FA Felipe… - Naunyn-Schmiedeberg's …, 2020 - Springer
The aim of this present study was to evaluate the effect of solid lipid nanoparticles (SLN)
containing carvacrol over the lung damage of airway smoke inhalation. The study was …

Molecular and cellular mechanisms of cigarette smoke-induced myocardial injury: prevention by vitamin C

A Das, N Dey, A Ghosh, S Das, DJ Chattopadhyay… - 2012 - journals.plos.org
Background Cardiovascular disease (CVD) remains one of the major killers in modern
society. One strong risk factor of CVD is cigarette smoking that causes myocardial injury and …

Cigarette smoke induces p-benzoquinone–albumin adduct in blood serum: implications on structure and ligand binding properties

A Ghosh, A Choudhury, A Das, NS Chatterjee, T Das… - Toxicology, 2012 - Elsevier
Earlier we had reported that irrespective of the source cigarette smoke (CS) contains
substantial amounts of p-benzosemiquinone, which is readily converted to p-benzoquinone …

Pathophysiological scenario of hematopoietic disorders: a comparative study of aplastic anemia, myelodysplastic syndrome and leukemia in experimental animals

R Chatterjee, S Chattopadhyay, S Sanyal… - Proceedings of the …, 2016 - Springer
The conversion of physiology to pathophysiology in hematological disorders viz: aplastic
anemia, myelodysplastic syndrome (MDS) and leukemia in murine models was the subject …

Analysis of hematopathology and alteration of JAK1/STAT3/STAT5 signaling axis in experimental myelodysplastic syndrome

S Daw, R Chatterjee, A Law, S Law - Chemico-Biological Interactions, 2016 - Elsevier
Hematological disorders like myelodysplastic syndrome (MDS) may arise due to cumulative
dysregulation of various signalling pathways controlling proliferation, differentiation …

L-ascorbic acid and α-tocopherol treatment alleviates parabenzoquinone-induced hemato-biochemical and histopathological changes in Wistar rats

R Mishra, K Dutta, MK Bharali - Toxicology and Environmental Health …, 2022 - Springer
Objective The effect of L-ascorbic acid and α-tocopherol on parabenzoquinone (p-BQ)-
induced hemato-biochemical and histological alterations in the liver and kidney of male …

p-Benzoquinone-induced aggregation and perturbation of structure and chaperone function of α-crystallin is a causative factor of cigarette smoke-related …

A Chowdhury, A Choudhury, S Chakraborty, A Ghosh… - Toxicology, 2018 - Elsevier
Cigarette smoking is a significant risk factor for cataract. However, the mechanism by which
cigarette smoke (CS) causes cataract remains poorly understood. We had earlier shown that …

Hematopathological alterations of major tumor suppressor cascade, vital cell cycle inhibitors and hematopoietic niche components in experimental myelodysplasia

R Chatterjee, S Gupta, S Law - Chemico-Biological Interactions, 2017 - Elsevier
Myelodysplastic syndrome (MDS) is a poorly understood dreadful hematopoietic disorder
that involves maturational defect and abnormalities in blood cell production leading to …

[HTML][HTML] p-Benzoquinone initiates non-invasive urothelial cancer through aberrant tyrosine phosphorylation of EGFR, MAP kinase activation and cell cycle …

S Ganguly, A Chandra, DJ Chattopadhyay… - Toxicology reports, 2017 - Elsevier
According to WHO classification system, non-invasive urothelial carcinoma represents
urothelial carcinoma in situ (CIS) and dysplasia. Dysplastic urothelium often progresses to …