The actin cytoskeleton responds to inflammatory cues and alters macrophage activation

E Ronzier, AJ Laurenson, R Manickam, S Liu… - Cells, 2022 - mdpi.com
Much remains to be learned about the molecular mechanisms underlying a class of human
disorders called actinopathies. These genetic disorders are characterized by loss-of-function …

A History and Atlas of the Human CD4+ T Helper Cell

JM Crater, DC Dunn, DF Nixon, RL Furler O'Brien - Biomedicines, 2023 - mdpi.com
CD4+ T cells have orchestrated and regulated immunity since the introduction of jawed
vertebrates, yet our understanding of CD4+ T cell evolution, development, and cellular …

The clinical phenotype with gastrostomy and abdominal wall infection in a pediatric patient with Takenouchi-Kosaki syndrome due to a heterozygous c. 191A> G (p …

A Szczawińska-Popłonyk, N Popłonyk… - Frontiers in …, 2023 - frontiersin.org
The CDC42 (cell division cycle homolog 42) gene product, Cdc42 belongs to the Rho
GTPase family which plays a pivotal role in the regulation of multiple cellular functions …

A Novel CDC42 Variant with Impaired Thymopoiesis, IL-7R Signaling, PAK1 Binding, and TCR Repertoire Diversity

K Assing, SE Jørgensen, KS Sandgaard… - Journal of Clinical …, 2023 - Springer
Genetic variants in cell division cycle 42 (CDC42) can manifest with dysmorphic features,
autoinflammation, hemophagocytic lymphohistiocytosis, and thrombocytopenia, whereas …

Use of a network-based method to identify latent genes associated with hearing loss in children

F Liang, X Fu, SJ Ding, L Li - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Hearing loss is a total or partial inability to hear. Approximately 5% of people worldwide
experience this condition. Hearing capacity is closely related to language, social, and basic …

OPEN ACCESS EDITED BY

S Wan, L He, Y Wang, X Huang, J Luo… - … Analysis of Omics …, 2023 - books.google.com
Background: Esophageal cancer is a tumor type with high invasiveness and low prognosis.
As immunotherapy has been shown to improve the prognosis of esophageal cancer …