Flavonoids as promising anticancer therapeutics: Contemporary research, nanoantioxidant potential, and future scope

M Gupta, J Ahmad, J Ahamad, S Kundu… - Phytotherapy …, 2023 - Wiley Online Library
Flavonoids are natural polyphenolic compounds considered safe, pleiotropic, and readily
available molecules. It is widely distributed in various food products such as fruits and …

Metal nanoparticle-flavonoid connections: synthesis, physicochemical and biological properties, as well as potential applications in medicine

S Sysak, B Czarczynska-Goslinska, P Szyk… - Nanomaterials, 2023 - mdpi.com
Flavonoids are polyphenolic compounds widely occurring throughout the plant kingdom.
They are biologically active and have many medical applications. Flavonoids reveal …

Deciphering molecular landscape of breast cancer progression and insights from functional genomics and therapeutic explorations followed by in vitro validation

B Khan, R Qahwaji, MS Alfaifi, T Athar, A Khan… - Scientific Reports, 2024 - nature.com
Breast cancer is caused by aberrant breast cells that proliferate and develop into tumors.
Tumors have the potential to spread throughout the body and become lethal if ignored …

NF-kB in signaling patterns and its temporal dynamics encode/decode human diseases

S Almowallad, LS Alqahtani, M Mobashir - Life, 2022 - mdpi.com
Defects in signaling pathways are the root cause of many disorders. These malformations
come in a wide variety of types, and their causes are also very diverse. Some of these flaws …

An approach for systems-level understanding of prostate cancer from high-throughput data integration to pathway modeling and simulation

M Mobashir, SP Turunen, MA Izhari, IM Ashankyty… - Cells, 2022 - mdpi.com
To understand complex diseases, high-throughput data are generated at large and multiple
levels. However, extracting meaningful information from large datasets for comprehensive …

Fungal-mediated silver nanoparticle and biochar synergy against colorectal cancer cells and pathogenic bacteria

M Alqaraleh, KM Khleifat, MN Abu Hajleh, HS Farah… - Antibiotics, 2023 - mdpi.com
Background: Silver nanoparticles (AgNPs) are attractive substrates for new medicinal
treatments. Biochar is pyrolyzed biomass. Its porous architecture allows it to hold and gather …

Impact of curcumin on ferroptosis‐related genes in colorectal cancer: Insights from in‐silico and in‐vitro studies

AA Firouzjaei, SH Aghaee‐Bakhtiari… - Cell Biochemistry …, 2023 - Wiley Online Library
Colorectal cancer (CRC) is responsible for a significant number of cancer‐related fatalities
worldwide. Researchers are investigating the therapeutic potential of ferroptosis, a type of …

Genomic profiling and network-level understanding uncover the potential genes and the pathways in hepatocellular carcinoma

SA El-Kafrawy, MM El-Daly, LH Bajrai… - Frontiers in …, 2022 - frontiersin.org
Data integration with phenotypes such as gene expression, pathways or function, and
protein-protein interactions data has proven to be a highly promising technique for …

Myricetin-based fluorescence probes with AIE and ESIPT properties for detection of hydrazine in the environment and fingerprinting

W Xiao, Q Zhang, DH You, W Xue, F Peng, NB Li… - Analytica chimica …, 2024 - Elsevier
Abstract Background Hydrazine (N 2 H 4) is a highly toxic and versatile chemical raw
material, which poses a serious threat to the environment and human health when used in …

[PDF][PDF] Systems-level understanding of toxicology and cardiovascular system

S Almowallad, R Jeet, M Mobashir - Jour. Bas. Sci, 2024 - researchgate.net
The extensive networks of molecular and functional alterations that take place at many
levels of biological structure are studied using traditional toxicology and quantitative …