Deciphering cell–cell interactions and communication from gene expression
E Armingol, A Officer, O Harismendy… - Nature Reviews …, 2021 - nature.com
Cell–cell interactions orchestrate organismal development, homeostasis and single-cell
functions. When cells do not properly interact or improperly decode molecular messages …
functions. When cells do not properly interact or improperly decode molecular messages …
Initial recommendations for performing, benchmarking and reporting single-cell proteomics experiments
Analyzing proteins from single cells by tandem mass spectrometry (MS) has recently
become technically feasible. While such analysis has the potential to accurately quantify …
become technically feasible. While such analysis has the potential to accurately quantify …
Single-cell transcriptomic characterization of a gastrulating human embryo
RCV Tyser, E Mahammadov, S Nakanoh, L Vallier… - Nature, 2021 - nature.com
Gastrulation is the fundamental process in all multicellular animals through which the basic
body plan is first laid down,,–. It is pivotal in generating cellular diversity coordinated with …
body plan is first laid down,,–. It is pivotal in generating cellular diversity coordinated with …
scAAGA: Single cell data analysis framework using asymmetric autoencoder with gene attention
In recent years, single-cell RNA sequencing (scRNA-seq) has emerged as a powerful
technique for investigating cellular heterogeneity and structure. However, analyzing scRNA …
technique for investigating cellular heterogeneity and structure. However, analyzing scRNA …
Bacterial droplet-based single-cell RNA-seq reveals antibiotic-associated heterogeneous cellular states
P Ma, HM Amemiya, LL He, SJ Gandhi, R Nicol… - Cell, 2023 - cell.com
We introduce BacDrop, a highly scalable technology for bacterial single-cell RNA
sequencing that has overcome many challenges hindering the development of scRNA-seq …
sequencing that has overcome many challenges hindering the development of scRNA-seq …
High-throughput total RNA sequencing in single cells using VASA-seq
Most methods for single-cell transcriptome sequencing amplify the termini of polyadenylated
transcripts, capturing only a small fraction of the total cellular transcriptome. This precludes …
transcripts, capturing only a small fraction of the total cellular transcriptome. This precludes …
Role of the gut–brain axis in energy and glucose metabolism
HR Wachsmuth, SN Weninger, FA Duca - Experimental & molecular …, 2022 - nature.com
The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …
diseases. During a meal, the gut provides crucial information to the brain regarding …
Direct cell reprogramming: approaches, mechanisms and progress
The reprogramming of somatic cells with defined factors, which converts cells from one
lineage into cells of another, has greatly reshaped our traditional views on cell identity and …
lineage into cells of another, has greatly reshaped our traditional views on cell identity and …
Pathway paradigms revealed from the genetics of inflammatory bowel disease
DB Graham, RJ Xavier - Nature, 2020 - nature.com
Inflammatory bowel disease (IBD) is a complex genetic disease that is instigated and
amplified by the confluence of multiple genetic and environmental variables that perturb the …
amplified by the confluence of multiple genetic and environmental variables that perturb the …
A human liver cell atlas reveals heterogeneity and epithelial progenitors
The human liver is an essential multifunctional organ. The incidence of liver diseases is
rising and there are limited treatment options. However, the cellular composition of the liver …
rising and there are limited treatment options. However, the cellular composition of the liver …