Lab-on-a-chip devices for global health: Past studies and future opportunities

CD Chin, V Linder, SK Sia - Lab on a Chip, 2007 - pubs.rsc.org
A rapidly emerging field in lab-on-a-chip (LOC) research is the development of devices to
improve the health of people in developing countries. In this review, we identify diseases …

Application of microbioreactors in fermentation process development: a review

D Schäpper, MNHZ Alam, N Szita… - Analytical and …, 2009 - Springer
Biotechnology process development involves strain testing and improvement steps aimed at
increasing yields and productivity. This necessitates the high-throughput screening of many …

Dynamic single cell culture array

D Di Carlo, LY Wu, LP Lee - Lab on a Chip, 2006 - pubs.rsc.org
It is important to quantify the distribution of behavior amongst a population of individual cells
to reach a more complete quantitative understanding of cellular processes. Improved high …

A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics

CL Walsh, BM Babin, RW Kasinskas, JA Foster… - Lab on a Chip, 2009 - pubs.rsc.org
The heterogeneity of cellular microenvironments in tumors severely limits the efficacy of
most cancer therapies. We have designed a microfluidic device that mimics the …

Microfluidic in vitro platform for (nano) safety and (nano) drug efficiency screening

Y Kohl, M Biehl, S Spring, M Hesler, V Ogourtsov… - Small, 2021 - Wiley Online Library
Microfluidic technology is a valuable tool for realizing more in vitro models capturing cellular
and organ level responses for rapid and animal‐free risk assessment of new chemicals and …

Technique for the control of spheroid diameter using microfabricated chips

Y Sakai, K Nakazawa - Acta biomaterialia, 2007 - Elsevier
This paper describes a new technique for the control of spheroid diameter in liver-derived
cell lines using microfabricated chips that were prepared by combining microfabrication with …

Ethanol and UV-assisted instantaneous bonding of PMMA assemblies and tuning in bonding reversibility

HH Tran, W Wu, NY Lee - Sensors and Actuators B: Chemical, 2013 - Elsevier
Here, we introduce an instantaneous and robust strategy for bonding poly
(methylmethacrylate)(PMMA) substrates via ethanol treatment combined with subsequent …

High-precision temperature measurement based on weak measurement using nematic liquid crystals

H Li, JZ Huang, Y Yu, Y Li, C Fang, G Zeng - Applied Physics Letters, 2018 - pubs.aip.org
High-precision temperature measurements could guarantee temperature difference control
accuracy in research and industrial production. To flexibly achieve high precision and large …

Modernization of biosensing strategies for the development of lab‐on‐chip integrated systems

S Roy, SJ Malode, NP Shetti… - Bioelectrochemical …, 2019 - Wiley Online Library
A biosensor is an analytical device for modern biological detection processes by which
complications of procedures, time, and cost get reduced. Fabricating new biosensor devices …

Incubator-independent perfusion system integrated with microfluidic device for continuous electrophysiology and microscopy readouts

R Habibey - Biofabrication, 2023 - iopscience.iop.org
Advances in primary and stem cell derived neuronal cell culture techniques and abundance
of available neuronal cell types have enabled in vitro neuroscience as a substantial …