T-cell exhaustion in immune-mediated inflammatory diseases: New implications for immunotherapy
Z Gao, Y Feng, J Xu, J Liang - Frontiers in Immunology, 2022 - frontiersin.org
Immune-mediated inflammatory diseases (IMIDs) are referred to as highly disabling chronic
diseases affecting different organs and systems. Inappropriate or excessive immune …
diseases affecting different organs and systems. Inappropriate or excessive immune …
Soluble form of immune checkpoints in autoimmune diseases
L Yuan, Y Wang, X Shen, F Ma, J Wang, F Yan - Journal of Autoimmunity, 2024 - Elsevier
Immune checkpoints are essential regulators of immune responses, either by activating or
suppressing them. Consequently, they are regarded as pivotal elements in the management …
suppressing them. Consequently, they are regarded as pivotal elements in the management …
Soluble CD72, is a T-cell activator probably via binding to CD6 in homeostasis and autoimmunity
N Eiza, A Sabag, O Kessler, E Toubi… - Frontiers in …, 2024 - frontiersin.org
Background CD72 is a highly required regulatory molecule in B cells. Its sufficient
expression is crucial for maintaining self-tolerance. In contrast, soluble CD72 (sCD72) is …
expression is crucial for maintaining self-tolerance. In contrast, soluble CD72 (sCD72) is …
From bench to bedside: Targeting lymphocyte activation gene 3 as a therapeutic strategy for autoimmune diseases
X Zhou, Y Gu, H Wang, W Zhou, L Zou, S Li, C Hua… - Inflammation …, 2023 - Springer
Background Immune checkpoints negatively regulate immune response, thereby playing an
important role in maintaining immune homeostasis. Substantial studies have confirmed that …
important role in maintaining immune homeostasis. Substantial studies have confirmed that …
Exploring the molecular landscape of lymphocyte activation gene-3: A literature review
J Nie, X Qin, X Tao, J Huang - Medicine, 2024 - journals.lww.com
Molecular structure and cellular distribution of lymphocyte activation gene-3 (LAG-3) have
been studied extensively since 1990. However, several unresolved questions remain. It is …
been studied extensively since 1990. However, several unresolved questions remain. It is …
Comprehensive Co-inhibitory Receptors (Co-IRS) Expression T Cells and Soluble Proteins Predict Ra Pathogenesis and Activity
CM Wang, YJJ Wu, LY Huang, JW Zheng, JY Chen - 2024 - preprints.org
Abstract Co-inhibitory receptors (Co-IRs) are essential in controlling the progression of
immunopathology in rheumatoid arthritis (RA) by limiting T cell activation. The objective of …
immunopathology in rheumatoid arthritis (RA) by limiting T cell activation. The objective of …
[PDF][PDF] Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
REP MELÉNDEZ - 2023 - ru.dgb.unam.mx
UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO INSTITUTO NACIONAL DE CIENCIAS
MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN USO DE LA FOTOG Page 1 UNIVERSIDAD …
MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN USO DE LA FOTOG Page 1 UNIVERSIDAD …
Investigating the immunophenotype unique to interstitial lung disease in systemic autoimmune rheumatic diseases
JE Kim - 2023 - search.proquest.com
Systemic autoimmune rheumatic diseases (SARDs) involve immune dysregulation and a
disruption to self-tolerance. Typical SARDs include rheumatoid arthritis (RA), systemic lupus …
disruption to self-tolerance. Typical SARDs include rheumatoid arthritis (RA), systemic lupus …