Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases

MJ Betts, E Kirilina, MCG Otaduy, D Ivanov… - Brain, 2019 - academic.oup.com
Pathological alterations to the locus coeruleus, the major source of noradrenaline in the
brain, are histologically evident in early stages of neurodegenerative diseases. Novel MRI …

Development and evolution of cerebral and cerebellar cortex

DC Van Essen, CJ Donahue, MF Glasser - Brain Behavior and …, 2018 - karger.com
Cerebral cortex and cerebellar cortex both vary enormously across species in their size and
complexity of convolutions. We discuss the development and evolution of cortical structures …

Mapping neurotransmitter systems to the structural and functional organization of the human neocortex

JY Hansen, G Shafiei, RD Markello, K Smart… - Nature …, 2022 - nature.com
Neurotransmitter receptors support the propagation of signals in the human brain. How
receptor systems are situated within macro-scale neuroanatomy and how they shape …

Topographic organization of the human subcortex unveiled with functional connectivity gradients

Y Tian, DS Margulies, M Breakspear, A Zalesky - Nature neuroscience, 2020 - nature.com
Brain atlases are fundamental to understanding the topographic organization of the human
brain, yet many contemporary human atlases cover only the cerebral cortex, leaving the …

Meningeal lymphatic vessels at the skull base drain cerebrospinal fluid

JH Ahn, H Cho, JH Kim, SH Kim, JS Ham, I Park… - Nature, 2019 - nature.com
Recent work has shown that meningeal lymphatic vessels (mLVs), mainly in the dorsal part
of the skull, are involved in the clearance of cerebrospinal fluid (CSF), but the precise route …

Dynamic modulation of decision biases by brainstem arousal systems

JW de Gee, O Colizoli, NA Kloosterman, T Knapen… - elife, 2017 - elifesciences.org
Decision-makers often arrive at different choices when faced with repeated presentations of
the same evidence. Variability of behavior is commonly attributed to noise in the brain's …

A unified 3D map of microscopic architecture and MRI of the human brain

A Alkemade, PL Bazin, R Balesar, K Pine, E Kirilina… - Science …, 2022 - science.org
We present the first three-dimensional (3D) concordance maps of cyto-and fiber architecture
of the human brain, combining histology, immunohistochemistry, and 7-T quantitative …

Real-world stress resilience is associated with the responsivity of the locus coeruleus

M Grueschow, N Stenz, H Thörn, U Ehlert… - Nature …, 2021 - nature.com
Individuals may show different responses to stressful events. Here, we investigate the
neurobiological basis of stress resilience, by showing that neural responsitivity of the …

A causal role of anterior prefrontal-putamen circuit for response inhibition revealed by transcranial ultrasound stimulation in humans

K Nakajima, T Osada, A Ogawa, M Tanaka, S Oka… - Cell Reports, 2022 - cell.com
Stopping an inappropriate response requires the involvement of the prefrontal-subthalamic
hyperdirect pathway. However, how the prefrontal-striatal indirect pathway contributes to …

[HTML][HTML] Microstructural imaging of human neocortex in vivo

LJ Edwards, E Kirilina, S Mohammadi, N Weiskopf - Neuroimage, 2018 - Elsevier
The neocortex of the human brain is the seat of higher brain function. Modern imaging
techniques, chief among them magnetic resonance imaging (MRI), allow non-invasive …