Humans in modern societies typically consume food at least three times daily, while
laboratory animals are fed ad libitum. Overconsumption of food with such eating patterns …

Background: Intermittent fasting, alternate-day fasting, and other forms of periodic caloric
desistance are gaining popularity in the lay press and among animal research scientists …

The COVID-19 pandemic is an unprecedented health crisis as entire populations have been
asked to self-isolate and live in home-confinement for several weeks to months, which in …

Cognitive decline is one of the complications of type 2 diabetes (T2D). Intermittent fasting
(IF) is a promising dietary intervention for alleviating T2D symptoms, but its protective effect …

Multiple sclerosis (MS) is more common in western countries with diet being a potential
contributing factor. Here we show that intermittent fasting (IF) ameliorated clinical course and …

Glial activation and neuroinflammation play significant roles in apoptosis as well as in the
development of cognitive and memory deficits. Neuroinflammation is also a critical feature in …

Microglia-induced neuroinflammation plays a vital role in the etiology and progression of
neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and …

Alzheimer's disease (AD) is one of the fastest growing cognitive decline-related neurological
diseases. To date, effective curative strategies have remained elusive. A growing body of …

Parkinson's disease (PD) is strongly associated with life style, especially dietary habits,
which have gained attention as disease modifiers. Here, we report a fasting mimicking diet …

Aging is the major risk factor for neurodegenerative diseases, accelerated by excessive
calorie consumption and sedentary lifestyles. Bioenergetic challenges such as intermittent …