Force spectroscopy of single cells using atomic force microscopy
Physical forces and mechanical properties have critical roles in cellular function, physiology
and disease. Over the past decade, atomic force microscopy (AFM) techniques have …
and disease. Over the past decade, atomic force microscopy (AFM) techniques have …
Biophysical approaches for applying and measuring biological forces
Over the past decades, increasing evidence has indicated that mechanical loads can
regulate the morphogenesis, proliferation, migration, and apoptosis of living cells …
regulate the morphogenesis, proliferation, migration, and apoptosis of living cells …
New mechanical markers for tracking the progression of myocardial infarction
The mechanical properties of soft tissues can often be strongly correlated with the
progression of various diseases, such as myocardial infarction (MI). However, the dynamic …
progression of various diseases, such as myocardial infarction (MI). However, the dynamic …
Viscoelastic multiscale mechanical indexes for assessing liver fibrosis and treatment outcomes
Understanding liver tissue mechanics, particularly in the context of liver pathologies like
fibrosis, cirrhosis, and carcinoma, holds pivotal significance for assessing disease severity …
fibrosis, cirrhosis, and carcinoma, holds pivotal significance for assessing disease severity …
Mechanical stimulation and electrophysiological monitoring at subcellular resolution reveals differential mechanosensation of neurons within networks
A growing consensus that the brain is a mechanosensitive organ is driving the need for tools
that mechanically stimulate and simultaneously record the electrophysiological response of …
that mechanically stimulate and simultaneously record the electrophysiological response of …
Silk fibroin, gelatin, and human placenta extracellular matrix-based composite hydrogels for 3D bioprinting and soft tissue engineering
Background There is a great clinical need and it remains a challenge to develop artificial soft
tissue constructs that can mimic the biomechanical properties and bioactivity of natural …
tissue constructs that can mimic the biomechanical properties and bioactivity of natural …
Branched actin cortices reconstituted in vesicles sense membrane curvature
The actin cortex is a complex cytoskeletal machinery that drives and responds to changes in
cell shape. It must generate or adapt to plasma membrane curvature to facilitate diverse …
cell shape. It must generate or adapt to plasma membrane curvature to facilitate diverse …
Viscoelastic properties of epithelial cells
A Janshoff - Biochemical Society Transactions, 2021 - portlandpress.com
Epithelial cells form tight barriers that line both the outer and inner surfaces of organs and
cavities and therefore face diverse environmental challenges. The response to these …
cavities and therefore face diverse environmental challenges. The response to these …
How do cells stiffen?
Cell stiffness is an important characteristic of cells and their response to external stimuli. In
this review, we survey methods used to measure cell stiffness, summarize stimuli that alter …
this review, we survey methods used to measure cell stiffness, summarize stimuli that alter …
Monitoring the mass, eigenfrequency, and quality factor of mammalian cells
S Herzog, G Fläschner, I Incaviglia, JC Arias… - Nature …, 2024 - nature.com
The regulation of mass is essential for the development and homeostasis of cells and
multicellular organisms. However, cell mass is also tightly linked to cell mechanical …
multicellular organisms. However, cell mass is also tightly linked to cell mechanical …