The somatosensory system mediates fundamental physiological functions, including the
senses of touch, pain and proprioception. This variety of functions is matched by a diverse …

Neurons that sense touch, sound and acceleration respond rapidly to specific mechanical
signals. The proteins that transduce these signals and underlie these senses, however, are …

In sensory neurons, mechanotransduction is sensitive, fast and requires mechanosensitive
ion channels. Here we develop a new method to directly monitor mechanotransduction at …

Mechanosensitive ion channels are gated directly by physical stimuli and transduce these
stimuli into electrical signals. Several criteria must apply for a channel to be considered …

Sensing force is crucial to maintain the viability of all living cells. Despite its fundamental
importance, how force is sensed at the molecular level remains largely unknown. Here we …

The sense of touch detects forces that bombard the body's surface. In metazoans, an
assortment of morphologically and functionally distinct mechanosensory cell types are tuned …

This review article focuses on quenching of bacterial quorum sensing (QS) signaling by
macromolecules. Although various research efforts have led to the design and identification …

The senses of proprioception, touch, hearing, and blood pressure on mechanosensitive ion
channels that transduce mechanical stimuli with high sensitivity and speed. This conversion …

A growing body of work suggests that the material properties of biomolecular condensates
ensuing from liquid–liquid phase separation change with time. How this aging process is …

Mechanoelectrical transduction (MeT) channels embedded in neuronal cell membranes are
essential for touch and proprioception. Little is understood about the interplay between …