Immunopolymorphism is considered as an important aspect behind the resistance or
susceptibility of the host to an infectious disease. Over the years, researchers have explored …

In the year 2000, cytomegalovirus was identified as a risk factor for mortality in a seminal
study of octogenarian residents in Sweden. This finding triggered a wave of additional …

Human cytomegalovirus (HCMV) is a ubiquitous herpes virus (human herpes virus 5) with
the highest morbidity and mortality rates compared to other herpes viruses. Risk groups …

Ovarian cancer (OC) is one of the most common cancers threatening women's lives around
the world. Epithelial ovarian tumors represent the most common ovarian neoplasms. Most …

Toll-like receptors (TLRs) recognize pathogen-associated molecular patterns and activate
innate and adaptive immune responses. Single nucleotide polymorphisms (SNPs) within the …

Abstract Introduction: Vertical transmission of Cytomegalovirus (CMV), resulting in
congenital CMV (cCMV) infection could have disabling and potentially fatal effects on the …

Toll-like receptor 9 (TLR9) recognizes non-methylated viral CpG-containing DNA and serves
as a pattern recognition receptor that signals the presence of human cytomegalovirus …

Intracellular Toll-like receptor 3 (TLR3) recognizes viral double-stranded RNA (dsRNA) and
activates antiviral immune responses through the production of type I interferons (IFNs) and …

Approximately, up to 70% of the human population is infected with cytomegalovirus (CMV)
that persists for life in a latent state. In healthy people, CMV reactivation induces the …

Patients who present with severe intractable apparently idiopathic fatigue accompanied by
profound physical and or cognitive disability present a significant therapeutic challenge. The …