[HTML][HTML] CXCL13-CXCR5 axis: Regulation in inflammatory diseases and cancer

B Wang, M Wang, D Ao, X Wei - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Chemokine CXC motif ligand 13 (CXCL13), originally identified as a B-cell chemokine, plays
an important role in the immune system. The interaction between CXCL13 and its receptor …

Translating biosynthetic gene clusters into fungal armor and weaponry

NP Keller - Nature chemical biology, 2015 - nature.com
Filamentous fungi are renowned for the production of a diverse array of secondary
metabolites (SMs) where the genetic material required for synthesis of a SM is typically …

[HTML][HTML] What are the 100 most cited fungal genera?

CS Bhunjun, YJ Chen, C Phukhamsakda… - Studies in …, 2024 - ingentaconnect.com
The global diversity of fungi has been estimated between 2 to 11 million species, of which
only about 155 000 have been named. Most fungi are invisible to the unaided eye, but they …

How far have we explored fungi to fight cancer?

CW How, YS Ong, SS Low, A Pandey, PL Show… - Seminars in cancer …, 2022 - Elsevier
The use of fungal cultures have been well documented in human history. Although its used
in healthcare, like penicillin and statins, have saved countless of lives, but there is still no …

Correlations between microbiota bioactivity and bioavailability of functional compounds: A mini-review

E Vamanu, F Gatea - Biomedicines, 2020 - mdpi.com
Numerous studies have demonstrated the role of the microbiota in supporting the
physiological functions, owing to its metabolomic component. The presence of …

Targeting the sphingosine kinase/sphingosine-1-phosphate signaling axis in drug discovery for cancer therapy

P Gupta, A Taiyab, A Hussain, MF Alajmi, A Islam… - Cancers, 2021 - mdpi.com
Simple Summary Cancer is the prime cause of death globally. The altered stimulation of
signaling pathways controlled by human kinases has often been observed in various human …

Bio-nanocarriers for lung cancer management: Befriending the barriers

S Rawal, M Patel - Nano-Micro Letters, 2021 - Springer
Lung cancer is a complex thoracic malignancy developing consequential to aberrations in a
myriad of molecular and biomolecular signaling pathways. It is one of the most lethal forms …

[HTML][HTML] Natural resorcylic acid lactones: A chemical biology approach for anticancer activity

S Kuttikrishnan, KS Prabhu, AH Al Sharie… - Drug Discovery …, 2022 - Elsevier
Resorcylic acid lactones (RALs) are fungal polyketides that consist of a β-resorcylic acid
residue (2, 4-dihydroxybenzoic acid) embedded in a macrolactone ring. RALs exhibit a …

Identification of sesquiterpene synthases from the Basidiomycota Coniophora puteana for the efficient and highly selective β-copaene and cubebol production in E …

W Mischko, M Hirte, M Fuchs, N Mehlmer… - Microbial cell …, 2018 - Springer
Background Terpenes are an important and extremely versatile class of secondary
metabolites that are commercially used in the pharmaceutical, food and cosmetics sectors …

Fungal depsides—Naturally inspiring molecules: Biosynthesis, structural characterization, and biological activities

SRM Ibrahim, A Sirwi, BG Eid, SGA Mohamed… - Metabolites, 2021 - mdpi.com
Fungi represent a huge reservoir of structurally diverse bio-metabolites. Although there has
been a marked increase in the number of isolated fungal metabolites over the past years …