Photoluminescent nanoparticles for chemical and biological analysis and imaging

WR Algar, M Massey, K Rees, R Higgins… - Chemical …, 2021 - ACS Publications
Research related to the development and application of luminescent nanoparticles (LNPs)
for chemical and biological analysis and imaging is flourishing. Novel materials and new …

Protein nanoparticles: promising platforms for drug delivery applications

A Jain, SK Singh, SK Arya, SC Kundu… - … Biomaterials Science & …, 2018 - ACS Publications
The development of drug delivery systems using nanoparticles as carriers for small and
large therapeutic molecules remains a rapidly growing area of research. The advantages of …

Virus‐like particles: Next‐generation nanoparticles for targeted therapeutic delivery

MJ Rohovie, M Nagasawa… - … & translational medicine, 2017 - Wiley Online Library
Most drug therapies distribute the agents throughout the entire body, even though the drugs
are typically only needed at specific tissues. This often limits dosage and causes discomfort …

Bioengineering strategies for protein-based nanoparticles

D Diaz, A Care, A Sunna - Genes, 2018 - mdpi.com
In recent years, the practical application of protein-based nanoparticles (PNPs) has
expanded rapidly into areas like drug delivery, vaccine development, and biocatalysis …

Quantitative packaging of active enzymes into a protein cage

Y Azuma, R Zschoche, M Tinzl… - Angewandte Chemie …, 2016 - Wiley Online Library
Genetic fusion of cargo proteins to a positively supercharged variant of green fluorescent
protein enables their quantitative encapsulation by engineered lumazine synthase capsids …

Enzyme encapsulation by a ferritin cage

S Tetter, D Hilvert - Angewandte Chemie International Edition, 2017 - Wiley Online Library
Ferritins, conserved across all kingdoms of life, are protein nanocages that evolved to
mineralize iron. The last several decades have shown that these cages have considerable …

Assembling enzymatic cascade pathways inside virus-based nanocages using dual-tasking nucleic acid tags

M Brasch, RM Putri, MV de Ruiter… - Journal of the …, 2017 - ACS Publications
The packaging of proteins into discrete compartments is an essential feature for cellular
efficiency. Inspired by Nature, we harness virus-like assemblies as artificial …

Emerging Solutions for in Vivo Biocatalyst Immobilization: Tailor-Made Catalysts for Industrial Biocatalysis

G Olcucu, O Klaus, KE Jaeger, T Drepper… - ACS Sustainable …, 2021 - ACS Publications
In industry, enzymes are often immobilized to generate more stable enzyme preparations
that are easier to store, handle, and recycle for repetitive use. Traditionally, enzymes are …

Plant virus-based materials for biomedical applications: Trends and prospects

S Eiben, C Koch, K Altintoprak, A Southan… - Advanced drug delivery …, 2019 - Elsevier
Nanomaterials composed of plant viral components are finding their way into medical
technology and health care, as they offer singular properties. Precisely shaped, tailored …

Protein cargo encapsulation by virus‐like particles: Strategies and applications

D McNeale, N Dashti, LC Cheah… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Viruses and the recombinant protein cages assembled from their structural proteins, known
as virus‐like particles (VLPs), have gained wide interest as tools in biotechnology and …