[HTML][HTML] Sustainable release of nerve growth factor for peripheral nerve regeneration using nerve conduits laden with Bioconjugated hyaluronic acid-chitosan …

H Xu, Y Yu, L Zhang, F Zheng, Y Yin, Y Gao, K Li… - Composites Part B …, 2022 - Elsevier
Peripheral nerve regeneration following injury is often incomplete, resulting in significant
personal and socioeconomic costs. Nerve conduits have been developed to complement or …

[HTML][HTML] Effects of dynamic mechanical stimulations on the regeneration of in vitro and in vivo cartilage tissue based on silk fibroin scaffold

M Gu, S Fan, G Zhou, K Ma, X Yao, Y Zhang - Composites Part B …, 2022 - Elsevier
Due to the lack of blood and nutrition supply, the repairing of cartilage defect has become a
challenging topic in clinical treatment. Herein, a unique porous scaffold based on …

Nanoengineered Endocytic Biomaterials for Stem Cell Therapy

Y Wang, C Sun, Z Liu, S Zhang, K Gao… - Advanced Functional …, 2024 - Wiley Online Library
Stem cells, ideal for the tissue repair and regeneration, possess extraordinary capabilities of
multidirectional differentiation and self‐renewal. However, the limited spontaneous …

Dual-modal imaging and synergistic spinal tumor therapy enabled by hierarchical-structured nanofibers with cascade release and postoperative anti-adhesion

J Qian, L Su, J He, R Ruan, J Wang, Z Wang, P Xiao… - ACS …, 2022 - ACS Publications
Most treatments for spinal cancer are accompanied by serious side effects including
subsequent tumor recurrence, spinal cord compression, and tissue adhesion, thus a highly …

Stemness maintenance and massproduction of neural stem cells on poly L‐lactic acid nanofibrous membrane based on piezoelectriceffect

X Lu, C Sun, L Chen, Z Feng, H Gao, S Hu, M Dong… - Small, 2022 - Wiley Online Library
Neural stem cells (NSCs) therapy is promising for treating neurodegenerative disorders and
neural injuries. However, the limited in vitro expansion, spontaneous differentiation, and …

1-and 2-dimensional (1 D/2 D) hydroxyapatite nanocrystals: A deep insight into synthesis strategies and multidimensional applications

U Kesarwani, B Basu, AK Dubey - Applied Materials Today, 2024 - Elsevier
Recently, one-and two-dimensional (1-and 2-D) hydroxyapatite (HA) nanocrystals gained
remarkable attention for their potential multifold performance in diverse areas such as, bone …

Multifunctional hydroxyapatite nanobelt haystacks integrated neural stem cell spheroid for rapid spinal cord injury repair

M Hao, L Chen, J He, X Zhao, H Xia… - Advanced Functional …, 2023 - Wiley Online Library
Due to the unwarranted lifespan and differentiation, applying neural stem cells (NSCs) in
spinal cord injury (SCI) remains challenging. In this study, 3D bioactive hydroxyapatite (HAp) …

HAp Thermosensitive Nanohydrogel Cavities Act as Brood Pouches to Incubate and Control‐Release NSCs for Rapid Spinal Cord Injury Therapy

M Hao, D Zhang, W Wang, Z Wei… - Advanced Functional …, 2022 - Wiley Online Library
Limitations such as the cell life span, cellular activity, and cellular diffusion outside the lesion
make the direct repair of spinal cord injury (SCI) by neural stem cell (NSC) transplantation …

Enhancing Bone Regeneration and Osteogenic Quality by n-HA Internalized Osteoblasts Synergized with ON Protein: Mechanistic Insights

W Yang, Q Zou, C Wang, Y Ren, R Zhang… - … Applied Materials & …, 2024 - ACS Publications
Bone scaffolds offer hope for oral jawbone repair, yet improving their osteogenic
performance remains a clinical challenge. This study investigates a novel approach to …

An injectable thermosensitive pluronic F127 loaded-nanohydroxyapatite/Polydopamine for promoting sciatic nerve repair after crush injury

L Kang, E Fang, M Gu, Y Guan, D Wu, X Zhang… - Colloids and Surfaces B …, 2025 - Elsevier
Peripheral nerve injury (PNI) remains an urgent issue due to its huge financial burden and
high rate of disability. Here, an injectable HAP/PDA thermosensitive pluronic F-127 (PF-127) …