Tumor extracellular matrix (ECM) not only forms a physical barrier for T cells infiltration, but
also regulates multiple immunosuppressive pathways, which is an important reason for …

Influenza A virus infection during pregnancy can cause adverse maternal and fetal
outcomes but the mechanism responsible remains elusive. Infection of outbred mice with …

Periodontitis is one of the most prevalent diseases in oral cavity, which could not merely
lead to the destruction of supporting or surrounding tooth structures but also affect the whole …

Problems Maternal chronic inflammation (MI) can adversely affect offspring's immune
development resulting in dysregulation of splenic T cells. Interleukin 1 beta (IL‐1β) …

Echinococcosis is a common human and animal parasitic disease that seriously endangers
human health and animal husbandry. Although studies have been conducted on vaccines …

Intrauterine inflammation (IUI) is the primary cause of spontaneous preterm birth and
predisposes neonates to long-term sequelae, including adverse neurological outcomes. N …

Tumor necrosis factor-α (TNF-α) antagonists are highly effective in controlling autoimmune
diseases. This has led to speculation that they might also be useful in treating inflammatory …

Uma abordagem científica essencial que tem sido central para o estudo da biologia e do
papel das células T CD8+ durante as respostas imunes é a melhor compreensão dos …