Solid-state nanopore sensors

L Xue, H Yamazaki, R Ren, M Wanunu… - Nature Reviews …, 2020 - nature.com
Nanopore-based sensors have established themselves as a prominent tool for solution-
based, single-molecule analysis of the key building blocks of life, including nucleic acids …

In situ solid-state nanopore fabrication

JP Fried, JL Swett, BP Nadappuram, JA Mol… - Chemical Society …, 2021 - pubs.rsc.org
Nanopores in solid-state membranes are promising for a wide range of applications
including DNA sequencing, ultra-dilute analyte detection, protein analysis, and polymer data …

Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping

KJ Freedman, LM Otto, AP Ivanov, A Barik… - Nature …, 2016 - nature.com
Single-molecule techniques are being developed with the exciting prospect of
revolutionizing the healthcare industry by generating vast amounts of genetic and proteomic …

The evolution of nanopore sequencing

Y Wang, Q Yang, Z Wang - Frontiers in genetics, 2015 - frontiersin.org
The “1000Genome”projecthasbeendrawingincreasingattention….Nanoporesequencing,
thethird-generation,isbelievedtobeoneofthemostpromisingsequ…“ 1000 Genome” while the …

Fabrication of electron tunneling probes for measuring single-protein conductance

T Jiang, L Yi, X Liu, AP Ivanov, JB Edel, L Tang - Nature Protocols, 2023 - nature.com
Studying the electrical properties of individual proteins is a prominent research area in the
field of bioelectronics. Electron tunnelling or quantum mechanical tunnelling (QMT) probes …

Combined quantum tunnelling and dielectrophoretic trapping for molecular analysis at ultra-low analyte concentrations

L Tang, BP Nadappuram, P Cadinu, Z Zhao… - Nature …, 2021 - nature.com
Quantum tunnelling offers a unique opportunity to study nanoscale objects with atomic
resolution using electrical readout. However, practical implementation is impeded by the …

Single-molecule analysis with solid-state nanopores

T Albrecht - Annual Review of Analytical Chemistry, 2019 - annualreviews.org
Solid-state nanopores and nanopipettes are an exciting class of single-molecule sensors
that has grown enormously over the last two decades. They offer a platform for testing …

Unsupervised vector-based classification of single-molecule charge transport data

M Lemmer, MS Inkpen, K Kornysheva, NJ Long… - Nature …, 2016 - nature.com
The stochastic nature of single-molecule charge transport measurements requires collection
of large data sets to capture the full complexity of a molecular system. Data analysis is then …

Solid-state nanopore localization by controlled breakdown of selectively thinned membranes

AT Carlsen, K Briggs, AR Hall… - Nanotechnology, 2017 - iopscience.iop.org
We demonstrate precise positioning of nanopores fabricated by controlled breakdown
(CBD) on solid-state membranes by spatially varying the electric field strength with localized …

Fabrication of solid‐state nanopores and its perspectives

J Kudr, S Skalickova, L Nejdl, A Moulick… - …, 2015 - Wiley Online Library
Nanofluidics is becoming an extensively developing technique in the field of bioanalytical
chemistry. Nanoscale hole embed in an insulating membrane is employed in a vast variety …