Immune system abnormalities in schizophrenia: an integrative view and translational perspectives

EA Ermakov, MM Melamud, VN Buneva… - Frontiers in …, 2022 - frontiersin.org
The immune system is generally known to be the primary defense mechanism against
pathogens. Any pathological conditions are reflected in anomalies in the immune system …

Immunoglobulins with non-canonical functions in inflammatory and autoimmune disease states

EA Ermakov, GA Nevinsky, VN Buneva - International journal of molecular …, 2020 - mdpi.com
Immunoglobulins are known to combine various effector mechanisms of the adaptive and
the innate immune system. Classical immunoglobulin functions are associated with antigen …

Probiotic and oxytocin combination therapy in patients with autism spectrum disorder: a randomized, double-blinded, placebo-controlled pilot trial

XJ Kong, J Liu, K Liu, M Koh, H Sherman, S Liu, R Tian… - Nutrients, 2021 - mdpi.com
Autism spectrum disorder (ASD) is a rapidly growing neurodevelopmental disorder. Both
probiotics and oxytocin were reported to have therapeutic potential; however, the …

PI3K/AKT/mTOR signalling inhibitor chrysophanol ameliorates neurobehavioural and neurochemical defects in propionic acid-induced experimental model of autism …

A Sharma, S Bhalla, S Mehan - Metabolic brain disease, 2022 - Springer
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder marked by
social and communication deficits as well as repetitive behaviour. Several studies have …

Probing disrupted neurodevelopment in autism using human stem cell‐derived neurons and organoids: An outlook into future diagnostics and drug development

G Yang, A Shcheglovitov - Developmental Dynamics, 2020 - Wiley Online Library
Autism spectrum disorders (ASDs) represent a spectrum of neurodevelopmental disorders
characterized by impaired social interaction, repetitive or restrictive behaviors, and problems …

Sex differences in neurodevelopmental disorders: a key role for the immune system

MR Breach, KM Lenz - Sex Differences in Brain Function and Dysfunction, 2022 - Springer
Sex differences are prominent defining features of neurodevelopmental disorders.
Understanding the sex biases in these disorders can shed light on mechanisms leading to …

Catalytic antibodies in bipolar disorder: serum IgGs hydrolyze myelin basic protein

DA Kamaeva, LP Smirnova, SN Vasilieva… - International Journal of …, 2022 - mdpi.com
The pathogenesis of bipolar affective disorder is associated with immunological imbalances,
a general pro-inflammatory status, neuroinflammation, and impaired white matter integrity …

Role of the immune system in autism spectrum disorders (ASD)

H Ormstad, V Bryn, OD Saugstad… - CNS & Neurological …, 2018 - ingentaconnect.com
Background: The evidence based supports that multifactorial and complex immune
interactions play a role in autism spectrum disorders (ASD), but contradictory findings are …

Some structural features of the peptide profile of myelin basic protein-hydrolyzing antibodies in schizophrenic patients

M Zavialova, D Kamaeva, L Kazieva, VS Skvortsov… - PeerJ, 2023 - peerj.com
The antibodies of schizophrenic patients that hydrolyze myelin basic protein (MBP) have
been actively studied recently, but the mechanism of the catalytic properties of …

Autoantibodies against myelin sheath and S100β are associated with cognitive dysfunction in patients with rheumatoid arthritis

TSA Baptista, LE Petersen, JK Molina, T de Nardi… - Clinical …, 2017 - Springer
Rheumatoid arthritis (RA) has been associated with cognitive impairment and peripheral
production of autoantibodies. Autoantibodies against central nervous system (CNS) proteins …